Treatment adherence, persistence, and effectiveness of fixed dose combination versus free combination therapy of rosuvastatin–ezetimibe as a lipid-lowering therapy

Treatment adherence, persistence, and effectiveness of fixed dose combination versus free combination therapy of rosuvastatin–ezetimibe as a lipid-lowering therapy

BackgroundGuidelines for dyslipidemia management recommend adding ezetimibe for patients with dyslipidemia inadequately controlled with statin monotherapy. A fixed-dose combination (FDC) of statin and ezetimibe may improve persistence and adherence and hence reduce LDL-C further compared to free-com...

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Bibliographic Details
Main Authors: Mihail Samnaliev, Irfan Khan, Praveen Potukuchi, Kelly Lee, Genevieve Garon, Charlie Nicholls
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
fixed-dose combination
free-combination treatment
single-pill combination
persistence
adherence
major adverse cardiovascular events
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1461416/full
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