IgM has a better relative distribution in inflammation sites and tumor tissues than IgG

IgM has a better relative distribution in inflammation sites and tumor tissues than IgG

Abstract Immunoglobulins (Igs) play a crucial role in host’s defense and in developing therapies against inflammatory diseases and cancer. Herein, we first studied the relative distribution of IgM and IgG in mouse models with acute or chronic inflammation. We found that IgM showed a more selective d...

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Bibliographic Details
Main Authors: Abdulaziz M. Aldayel, Mohammad Bosaeed, Sarah Almansour, Naif Khalaf Alharbi, Mohammed Alenazi, Haya A. Aljami, Omar Aldibasi, Abdulrhman Aljouie, Haiyue Xu, Zhengrong Cui
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Journal of Nanobiotechnology
Subjects:
Antibodies
Nanoparticle size
Distribution
Inflammation
Tumor
Online Access:https://doi.org/10.1186/s12951-025-03213-4
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