Posterior Reversible Encephalopathy Syndrome Associated with Tacrolimus in Cardiac Transplantation
Background. Neurological complications occur between 50 and 70% of patients with heart transplantation, including cerebrovascular events, infections, seizures, encephalopathy, and neurotoxicity due to pharmacological immunosuppression. Mortality associated with cerebrovascular complications is 7.5%...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Cardiology |
| Online Access: | http://dx.doi.org/10.1155/2021/9998205 |
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| author | Julián Alejandro Rivillas Stephania Galindo-Coral Francisco Arias-Mora Juan David Lopez-Ponce de Leon Noel Alberto Florez-Alarcón Pastor Olaya-Rojas Juan Esteban Gomez-Mesa |
| author_facet | Julián Alejandro Rivillas Stephania Galindo-Coral Francisco Arias-Mora Juan David Lopez-Ponce de Leon Noel Alberto Florez-Alarcón Pastor Olaya-Rojas Juan Esteban Gomez-Mesa |
| author_sort | Julián Alejandro Rivillas |
| collection | DOAJ |
| description | Background. Neurological complications occur between 50 and 70% of patients with heart transplantation, including cerebrovascular events, infections, seizures, encephalopathy, and neurotoxicity due to pharmacological immunosuppression. Mortality associated with cerebrovascular complications is 7.5% in the first 30 days and up to 5.3% after the first month and up to the first year after transplantation. Case Reports. Three heart-transplanted patients (2 men and 1 woman) treated with tacrolimus were identified. They presented with posterior reversible encephalopathy syndrome on days 5, 6, and 58 posttransplantation, respectively. In these reported cases, no sequelae were observed at 6 months follow-up. Conclusions. Posterior reversible encephalopathy syndrome as a neurological complication in patients with HT occurred early after the procedure. Early diagnosis and treatment might reduce the risk of serious complications and mortality. |
| format | Article |
| id | doaj-art-b020d71928cb4dfb81d15f16a8b17f4b |
| institution | Kabale University |
| issn | 2090-6404 2090-6412 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Cardiology |
| spelling | doaj-art-b020d71928cb4dfb81d15f16a8b17f4b2025-02-03T01:26:59ZengWileyCase Reports in Cardiology2090-64042090-64122021-01-01202110.1155/2021/99982059998205Posterior Reversible Encephalopathy Syndrome Associated with Tacrolimus in Cardiac TransplantationJulián Alejandro Rivillas0Stephania Galindo-Coral1Francisco Arias-Mora2Juan David Lopez-Ponce de Leon3Noel Alberto Florez-Alarcón4Pastor Olaya-Rojas5Juan Esteban Gomez-Mesa6Resident of Neurology, Universidad Icesi, Cali, ColombiaCardiology Department, Fundación Valle del Lili Hospital Universitario, Cali, ColombiaNeurology Department, Fundación Valle del Lili Hospital Universitario, Cali, ColombiaCardiology Department, Fundación Valle del Lili Hospital Universitario, Cali, ColombiaCardiology Department, Fundación Valle del Lili Hospital Universitario, Cali, ColombiaCardiology Department, Fundación Valle del Lili Hospital Universitario, Cali, ColombiaCardiology Department, Fundación Valle del Lili Hospital Universitario, Cali, ColombiaBackground. Neurological complications occur between 50 and 70% of patients with heart transplantation, including cerebrovascular events, infections, seizures, encephalopathy, and neurotoxicity due to pharmacological immunosuppression. Mortality associated with cerebrovascular complications is 7.5% in the first 30 days and up to 5.3% after the first month and up to the first year after transplantation. Case Reports. Three heart-transplanted patients (2 men and 1 woman) treated with tacrolimus were identified. They presented with posterior reversible encephalopathy syndrome on days 5, 6, and 58 posttransplantation, respectively. In these reported cases, no sequelae were observed at 6 months follow-up. Conclusions. Posterior reversible encephalopathy syndrome as a neurological complication in patients with HT occurred early after the procedure. Early diagnosis and treatment might reduce the risk of serious complications and mortality.http://dx.doi.org/10.1155/2021/9998205 |
| spellingShingle | Julián Alejandro Rivillas Stephania Galindo-Coral Francisco Arias-Mora Juan David Lopez-Ponce de Leon Noel Alberto Florez-Alarcón Pastor Olaya-Rojas Juan Esteban Gomez-Mesa Posterior Reversible Encephalopathy Syndrome Associated with Tacrolimus in Cardiac Transplantation Case Reports in Cardiology |
| title | Posterior Reversible Encephalopathy Syndrome Associated with Tacrolimus in Cardiac Transplantation |
| title_full | Posterior Reversible Encephalopathy Syndrome Associated with Tacrolimus in Cardiac Transplantation |
| title_fullStr | Posterior Reversible Encephalopathy Syndrome Associated with Tacrolimus in Cardiac Transplantation |
| title_full_unstemmed | Posterior Reversible Encephalopathy Syndrome Associated with Tacrolimus in Cardiac Transplantation |
| title_short | Posterior Reversible Encephalopathy Syndrome Associated with Tacrolimus in Cardiac Transplantation |
| title_sort | posterior reversible encephalopathy syndrome associated with tacrolimus in cardiac transplantation |
| url | http://dx.doi.org/10.1155/2021/9998205 |
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