Diagnostic and prognostic markers of oral squamous cell carcinoma- a detailed review
Oral Squamous Cell Carcinoma (OSCC) is one of the most common tumours of oral cavity. It has a high mortality and morbidity rate that can be greatly reduced by early diagnosis and intervention. The conventional diagnostic methods like biopsy may not aid in the early diagnosis of the lesion. It is at...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-06-01
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| Series: | Oral Oncology Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772906024001675 |
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| author | R. Ashwini Madhu Narayan K. Rajkumar |
| author_facet | R. Ashwini Madhu Narayan K. Rajkumar |
| author_sort | R. Ashwini |
| collection | DOAJ |
| description | Oral Squamous Cell Carcinoma (OSCC) is one of the most common tumours of oral cavity. It has a high mortality and morbidity rate that can be greatly reduced by early diagnosis and intervention. The conventional diagnostic methods like biopsy may not aid in the early diagnosis of the lesion. It is at this point that the tumor markers play an important role. Tumor markers relay information on current status of the lesion and also about the potential metastatic activity of the ongoing cancer. The ideal requirement of tumour marker should be that it must be sensitive and specific and it should not produce false negative and false positive results. Tumour markers should be easily available and it should be able to differentiate between non-neoplastic and neoplastic lesions. The tumour marker should be able to predict the recurrence and it should have a great prognostic value. This review article particularly focuses on various tumour markers pertaining to Oral Squamous Cell Carcinoma. We searched PubMed and Google Scholar for literature about tumour markers associated with OSCC published in English until December 2022 for this review. The pertinent data from the relevant papers were extracted and synthesised into a single review. |
| format | Article |
| id | doaj-art-b0202bac38eb4436ba2e30b2b2bd47ff |
| institution | Kabale University |
| issn | 2772-9060 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Oral Oncology Reports |
| spelling | doaj-art-b0202bac38eb4436ba2e30b2b2bd47ff2025-01-09T06:15:48ZengElsevierOral Oncology Reports2772-90602024-06-0110100321Diagnostic and prognostic markers of oral squamous cell carcinoma- a detailed reviewR. Ashwini0Madhu Narayan1K. Rajkumar2Corresponding author. SRM Dental College, Ramapuram, Chennai, India.; Department of Oral Pathology & Microbiology, SRM Dental College, SRMIST, Ramapuram, Chennai, IndiaDepartment of Oral Pathology & Microbiology, SRM Dental College, SRMIST, Ramapuram, Chennai, IndiaDepartment of Oral Pathology & Microbiology, SRM Dental College, SRMIST, Ramapuram, Chennai, IndiaOral Squamous Cell Carcinoma (OSCC) is one of the most common tumours of oral cavity. It has a high mortality and morbidity rate that can be greatly reduced by early diagnosis and intervention. The conventional diagnostic methods like biopsy may not aid in the early diagnosis of the lesion. It is at this point that the tumor markers play an important role. Tumor markers relay information on current status of the lesion and also about the potential metastatic activity of the ongoing cancer. The ideal requirement of tumour marker should be that it must be sensitive and specific and it should not produce false negative and false positive results. Tumour markers should be easily available and it should be able to differentiate between non-neoplastic and neoplastic lesions. The tumour marker should be able to predict the recurrence and it should have a great prognostic value. This review article particularly focuses on various tumour markers pertaining to Oral Squamous Cell Carcinoma. We searched PubMed and Google Scholar for literature about tumour markers associated with OSCC published in English until December 2022 for this review. The pertinent data from the relevant papers were extracted and synthesised into a single review.http://www.sciencedirect.com/science/article/pii/S2772906024001675Oral squamous cell carcinomaTumor markersDiagnosisPrognosis |
| spellingShingle | R. Ashwini Madhu Narayan K. Rajkumar Diagnostic and prognostic markers of oral squamous cell carcinoma- a detailed review Oral Oncology Reports Oral squamous cell carcinoma Tumor markers Diagnosis Prognosis |
| title | Diagnostic and prognostic markers of oral squamous cell carcinoma- a detailed review |
| title_full | Diagnostic and prognostic markers of oral squamous cell carcinoma- a detailed review |
| title_fullStr | Diagnostic and prognostic markers of oral squamous cell carcinoma- a detailed review |
| title_full_unstemmed | Diagnostic and prognostic markers of oral squamous cell carcinoma- a detailed review |
| title_short | Diagnostic and prognostic markers of oral squamous cell carcinoma- a detailed review |
| title_sort | diagnostic and prognostic markers of oral squamous cell carcinoma a detailed review |
| topic | Oral squamous cell carcinoma Tumor markers Diagnosis Prognosis |
| url | http://www.sciencedirect.com/science/article/pii/S2772906024001675 |
| work_keys_str_mv | AT rashwini diagnosticandprognosticmarkersoforalsquamouscellcarcinomaadetailedreview AT madhunarayan diagnosticandprognosticmarkersoforalsquamouscellcarcinomaadetailedreview AT krajkumar diagnosticandprognosticmarkersoforalsquamouscellcarcinomaadetailedreview |