Experimental Abdominal Sepsis: Sticking to an Awkward but Still Useful Translational Model
Animal models are widely used to replicate human intra-abdominal infections. Different methodologies have been described and proposed in the scientific literature, including injection and surgical models. The aim of this review is to recapitulate the advantages and disadvantages of each method to he...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2019-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2019/8971036 |
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| _version_ | 1832566564910530560 |
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| author | Federica Murando Andrea Peloso Lorenzo Cobianchi |
| author_facet | Federica Murando Andrea Peloso Lorenzo Cobianchi |
| author_sort | Federica Murando |
| collection | DOAJ |
| description | Animal models are widely used to replicate human intra-abdominal infections. Different methodologies have been described and proposed in the scientific literature, including injection and surgical models. The aim of this review is to recapitulate the advantages and disadvantages of each method to help choose the most appropriate model for individual experimental purposes. |
| format | Article |
| id | doaj-art-b018c89cfdc3400e8b48af594e57f8e5 |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-b018c89cfdc3400e8b48af594e57f8e52025-02-03T01:03:47ZengWileyMediators of Inflammation0962-93511466-18612019-01-01201910.1155/2019/89710368971036Experimental Abdominal Sepsis: Sticking to an Awkward but Still Useful Translational ModelFederica Murando0Andrea Peloso1Lorenzo Cobianchi2General Surgery Department, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, ItalyHepatology and Transplantation Laboratory, Department of Surgery, Faculty of Medicine, University of Geneva, Geneva, SwitzerlandGeneral Surgery Department, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, ItalyAnimal models are widely used to replicate human intra-abdominal infections. Different methodologies have been described and proposed in the scientific literature, including injection and surgical models. The aim of this review is to recapitulate the advantages and disadvantages of each method to help choose the most appropriate model for individual experimental purposes.http://dx.doi.org/10.1155/2019/8971036 |
| spellingShingle | Federica Murando Andrea Peloso Lorenzo Cobianchi Experimental Abdominal Sepsis: Sticking to an Awkward but Still Useful Translational Model Mediators of Inflammation |
| title | Experimental Abdominal Sepsis: Sticking to an Awkward but Still Useful Translational Model |
| title_full | Experimental Abdominal Sepsis: Sticking to an Awkward but Still Useful Translational Model |
| title_fullStr | Experimental Abdominal Sepsis: Sticking to an Awkward but Still Useful Translational Model |
| title_full_unstemmed | Experimental Abdominal Sepsis: Sticking to an Awkward but Still Useful Translational Model |
| title_short | Experimental Abdominal Sepsis: Sticking to an Awkward but Still Useful Translational Model |
| title_sort | experimental abdominal sepsis sticking to an awkward but still useful translational model |
| url | http://dx.doi.org/10.1155/2019/8971036 |
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