Report of a Rare Case of Gorham-Stout Disease of Both Shoulders: Bisphosphonate Treatment and Shoulder Replacement

Massive osteolysis known as Gorham-Stout disease is a rare idiopathic disorder typically affecting long bones in a unifocal pattern. Angiomatosis is strongly connected to the osteolysis. Weather angiomatosis is the cause or the result of osteolysis is subject of intense discussion (Kawasaki et al. (...

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Main Authors: Eike Garbers, Falk Reuther, Gunther Delling
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Rheumatology
Online Access:http://dx.doi.org/10.1155/2011/565142
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author Eike Garbers
Falk Reuther
Gunther Delling
author_facet Eike Garbers
Falk Reuther
Gunther Delling
author_sort Eike Garbers
collection DOAJ
description Massive osteolysis known as Gorham-Stout disease is a rare idiopathic disorder typically affecting long bones in a unifocal pattern. Angiomatosis is strongly connected to the osteolysis. Weather angiomatosis is the cause or the result of osteolysis is subject of intense discussion (Kawasaki et al. (2003), Möller et al. (1999), Radhakrishnan and Rockson (2008)). There are about 200 cases described since 1955. Our patient is a 77-year-old female patient with osteolyses of both shoulders involving the proximal humerus, lateral clavicle, and the glenoid. Under bisphosphonate therapy, the progressive osteolysis stopped on the right side and showed progression on the left. With the patient complaining about severe rest pain and impaired function, we performed surgical reconstruction by implantation of total shoulder prosthesis three months after onset of symptoms. Our case shows a possibility of primary and early surgical reconstruction with good clinical outcome.
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spelling doaj-art-b0100569d7c24d2d9610f9fe43a5ffce2025-08-20T03:39:15ZengWileyCase Reports in Rheumatology2090-68892090-68972011-01-01201110.1155/2011/565142565142Report of a Rare Case of Gorham-Stout Disease of Both Shoulders: Bisphosphonate Treatment and Shoulder ReplacementEike Garbers0Falk Reuther1Gunther Delling2Klinik für Unfallchirurgie und Orthopaedie, DRK Kliniken Berlin Koepenick, Salvador-Allende-Straße 2-8, 12559 Berlin, GermanyKlinik für Unfallchirurgie und Orthopaedie, DRK Kliniken Berlin Koepenick, Salvador-Allende-Straße 2-8, 12559 Berlin, GermanyInstitut für Pathologie Hannover, Berliner Allee 48, 30175 Hannover, GermanyMassive osteolysis known as Gorham-Stout disease is a rare idiopathic disorder typically affecting long bones in a unifocal pattern. Angiomatosis is strongly connected to the osteolysis. Weather angiomatosis is the cause or the result of osteolysis is subject of intense discussion (Kawasaki et al. (2003), Möller et al. (1999), Radhakrishnan and Rockson (2008)). There are about 200 cases described since 1955. Our patient is a 77-year-old female patient with osteolyses of both shoulders involving the proximal humerus, lateral clavicle, and the glenoid. Under bisphosphonate therapy, the progressive osteolysis stopped on the right side and showed progression on the left. With the patient complaining about severe rest pain and impaired function, we performed surgical reconstruction by implantation of total shoulder prosthesis three months after onset of symptoms. Our case shows a possibility of primary and early surgical reconstruction with good clinical outcome.http://dx.doi.org/10.1155/2011/565142
spellingShingle Eike Garbers
Falk Reuther
Gunther Delling
Report of a Rare Case of Gorham-Stout Disease of Both Shoulders: Bisphosphonate Treatment and Shoulder Replacement
Case Reports in Rheumatology
title Report of a Rare Case of Gorham-Stout Disease of Both Shoulders: Bisphosphonate Treatment and Shoulder Replacement
title_full Report of a Rare Case of Gorham-Stout Disease of Both Shoulders: Bisphosphonate Treatment and Shoulder Replacement
title_fullStr Report of a Rare Case of Gorham-Stout Disease of Both Shoulders: Bisphosphonate Treatment and Shoulder Replacement
title_full_unstemmed Report of a Rare Case of Gorham-Stout Disease of Both Shoulders: Bisphosphonate Treatment and Shoulder Replacement
title_short Report of a Rare Case of Gorham-Stout Disease of Both Shoulders: Bisphosphonate Treatment and Shoulder Replacement
title_sort report of a rare case of gorham stout disease of both shoulders bisphosphonate treatment and shoulder replacement
url http://dx.doi.org/10.1155/2011/565142
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