Isolation, Characterization and Antibacterial Activity Screening of Anthocyanidine Glycosides from Alchornea Cordifolia (Schumach. and Thonn.) Mull. Arg. Leaves

From the ethanolic extract of the leaves of Alchornea cordifolia (Schumach. and Thonn.) Mull. Arg,, 5–methyl 4’ -propenoxy anthocyanidines 7-O-β-D – diglucopyranoside was isolated. The structure was elucidated using NMR spectroscopy in combination with IR and MS spectral data. Antibacterial studies...

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Main Authors: Donatus Ebere Okwu, Nneka Ukanwa
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2010/586179
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author Donatus Ebere Okwu
Nneka Ukanwa
author_facet Donatus Ebere Okwu
Nneka Ukanwa
author_sort Donatus Ebere Okwu
collection DOAJ
description From the ethanolic extract of the leaves of Alchornea cordifolia (Schumach. and Thonn.) Mull. Arg,, 5–methyl 4’ -propenoxy anthocyanidines 7-O-β-D – diglucopyranoside was isolated. The structure was elucidated using NMR spectroscopy in combination with IR and MS spectral data. Antibacterial studies showed that the isolated compound successfully inhibited Pseudomonas aerguinosa, Escherichia coli, Proteus mirabilis, Klebsiella pueumonia and Staphylococcus aureus. This result authenticates the use of the plant in phytomedicine for disease prevention and treatment of infections.
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spelling doaj-art-b000cfc9c45f4143bc5a9eba5ceccf3b2025-08-20T03:39:17ZengWileyE-Journal of Chemistry0973-49452090-98102010-01-0171414810.1155/2010/586179Isolation, Characterization and Antibacterial Activity Screening of Anthocyanidine Glycosides from Alchornea Cordifolia (Schumach. and Thonn.) Mull. Arg. LeavesDonatus Ebere Okwu0Nneka Ukanwa1Department of Chemistry Michael Okpara University of Agriculture, Umudike, P.M.B. 7267 Umuahia, Abia State, NigeriaDepartment of Chemistry Michael Okpara University of Agriculture, Umudike, P.M.B. 7267 Umuahia, Abia State, NigeriaFrom the ethanolic extract of the leaves of Alchornea cordifolia (Schumach. and Thonn.) Mull. Arg,, 5–methyl 4’ -propenoxy anthocyanidines 7-O-β-D – diglucopyranoside was isolated. The structure was elucidated using NMR spectroscopy in combination with IR and MS spectral data. Antibacterial studies showed that the isolated compound successfully inhibited Pseudomonas aerguinosa, Escherichia coli, Proteus mirabilis, Klebsiella pueumonia and Staphylococcus aureus. This result authenticates the use of the plant in phytomedicine for disease prevention and treatment of infections.http://dx.doi.org/10.1155/2010/586179
spellingShingle Donatus Ebere Okwu
Nneka Ukanwa
Isolation, Characterization and Antibacterial Activity Screening of Anthocyanidine Glycosides from Alchornea Cordifolia (Schumach. and Thonn.) Mull. Arg. Leaves
E-Journal of Chemistry
title Isolation, Characterization and Antibacterial Activity Screening of Anthocyanidine Glycosides from Alchornea Cordifolia (Schumach. and Thonn.) Mull. Arg. Leaves
title_full Isolation, Characterization and Antibacterial Activity Screening of Anthocyanidine Glycosides from Alchornea Cordifolia (Schumach. and Thonn.) Mull. Arg. Leaves
title_fullStr Isolation, Characterization and Antibacterial Activity Screening of Anthocyanidine Glycosides from Alchornea Cordifolia (Schumach. and Thonn.) Mull. Arg. Leaves
title_full_unstemmed Isolation, Characterization and Antibacterial Activity Screening of Anthocyanidine Glycosides from Alchornea Cordifolia (Schumach. and Thonn.) Mull. Arg. Leaves
title_short Isolation, Characterization and Antibacterial Activity Screening of Anthocyanidine Glycosides from Alchornea Cordifolia (Schumach. and Thonn.) Mull. Arg. Leaves
title_sort isolation characterization and antibacterial activity screening of anthocyanidine glycosides from alchornea cordifolia schumach and thonn mull arg leaves
url http://dx.doi.org/10.1155/2010/586179
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