Efficacy of sivelestat in alleviating postoperative pulmonary injury in patients with acute aortic dissection undergoing total arch replacement: a retrospective cohort study

Efficacy of sivelestat in alleviating postoperative pulmonary injury in patients with acute aortic dissection undergoing total arch replacement: a retrospective cohort study

Abstract Objective Sivelestat may reduce postoperative pulmonary injury after total arch replacement (TAR). This study aimed to evaluate whether the preoperative PaO2/FiO2 (P/F) ratio affects the efficacy of sivelestat in reducing postoperative pulmonary injury in patients with acute aortic dissecti...

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Bibliographic Details
Main Authors: Zhiyan Mai, Xudong Liu, Weixun Duan, Chen Yang, Yenong Zhou, Tao Chen, Zheng Su, Yang Yang, Jincheng Liu, Zhenxiao Jin
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Cardiovascular Disorders
Subjects:
Sivelestat
PaO2/FiO2 ratio
Hypothermic circulatory arrest
Total arch replacement
Pulmonary injury
Online Access:https://doi.org/10.1186/s12872-025-04527-9
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