Nervous System of Periplaneta americana Cockroach as a Model in Toxinological Studies: A Short Historical and Actual View
Nervous system of Periplaneta americana cockroach is used in a wide range of pharmacological studies, including electrophysiological techniques. This paper presents its role as a preparation in the development of toxinological studies in the following electrophysiological methods: double-oil-gap tec...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Journal of Toxicology |
| Online Access: | http://dx.doi.org/10.1155/2012/143740 |
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| _version_ | 1832559786751688704 |
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| author | Maria Stankiewicz Marcin Dąbrowski Maria Elena de Lima |
| author_facet | Maria Stankiewicz Marcin Dąbrowski Maria Elena de Lima |
| author_sort | Maria Stankiewicz |
| collection | DOAJ |
| description | Nervous system of Periplaneta americana cockroach is used in a wide range of pharmacological studies, including electrophysiological techniques. This paper presents its role as a preparation in the development of toxinological studies in the following electrophysiological methods: double-oil-gap technique on isolated giant axon, patch-clamp on DUM (dorsal unpaired median) neurons, microelectrode technique in situ conditions on axon in connective and DUM neurons in ganglion, and single-fiber oil-gap technique on last abdominal ganglion synapse. At the end the application of cockroach synaptosomal preparation is mentioned. |
| format | Article |
| id | doaj-art-aff724f7b9c74f869040e40c88550fd4 |
| institution | Kabale University |
| issn | 1687-8191 1687-8205 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Toxicology |
| spelling | doaj-art-aff724f7b9c74f869040e40c88550fd42025-02-03T01:29:15ZengWileyJournal of Toxicology1687-81911687-82052012-01-01201210.1155/2012/143740143740Nervous System of Periplaneta americana Cockroach as a Model in Toxinological Studies: A Short Historical and Actual ViewMaria Stankiewicz0Marcin Dąbrowski1Maria Elena de Lima2Biophysics Laboratory, Institute of General and Molecular Biology, N. Copernicus University, 87-100 Torun, PolandBiophysics Laboratory, Institute of General and Molecular Biology, N. Copernicus University, 87-100 Torun, PolandDepartamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, 31270-901 MG, BrazilNervous system of Periplaneta americana cockroach is used in a wide range of pharmacological studies, including electrophysiological techniques. This paper presents its role as a preparation in the development of toxinological studies in the following electrophysiological methods: double-oil-gap technique on isolated giant axon, patch-clamp on DUM (dorsal unpaired median) neurons, microelectrode technique in situ conditions on axon in connective and DUM neurons in ganglion, and single-fiber oil-gap technique on last abdominal ganglion synapse. At the end the application of cockroach synaptosomal preparation is mentioned.http://dx.doi.org/10.1155/2012/143740 |
| spellingShingle | Maria Stankiewicz Marcin Dąbrowski Maria Elena de Lima Nervous System of Periplaneta americana Cockroach as a Model in Toxinological Studies: A Short Historical and Actual View Journal of Toxicology |
| title | Nervous System of Periplaneta americana Cockroach as a Model in Toxinological Studies: A Short Historical and Actual View |
| title_full | Nervous System of Periplaneta americana Cockroach as a Model in Toxinological Studies: A Short Historical and Actual View |
| title_fullStr | Nervous System of Periplaneta americana Cockroach as a Model in Toxinological Studies: A Short Historical and Actual View |
| title_full_unstemmed | Nervous System of Periplaneta americana Cockroach as a Model in Toxinological Studies: A Short Historical and Actual View |
| title_short | Nervous System of Periplaneta americana Cockroach as a Model in Toxinological Studies: A Short Historical and Actual View |
| title_sort | nervous system of periplaneta americana cockroach as a model in toxinological studies a short historical and actual view |
| url | http://dx.doi.org/10.1155/2012/143740 |
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