Case Report: Coexistence of an esophageal schwannoma disguised as a leiomyoma with a gastrointestinal stromal tumor of the gastric fundus

To our knowledge, this is the first reported case of coexisting esophageal schwannoma and gastric fundus gastrointestinal stromal tumor (GIST). This case report describes the diagnostic and treatment process of a patient with esophageal schwannoma who also had a concurrent gastric fundus GIST and wa...

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Main Authors: Yuedong Wang, Zhifei Xin, Wenbo Wu, Zhonghui Hu, Zhenghao Jia, Chengyao Zhang, Yi Ma, Xiaopeng Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1573436/full
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author Yuedong Wang
Yuedong Wang
Zhifei Xin
Wenbo Wu
Zhonghui Hu
Zhenghao Jia
Zhenghao Jia
Chengyao Zhang
Chengyao Zhang
Yi Ma
Yi Ma
Xiaopeng Zhang
author_facet Yuedong Wang
Yuedong Wang
Zhifei Xin
Wenbo Wu
Zhonghui Hu
Zhenghao Jia
Zhenghao Jia
Chengyao Zhang
Chengyao Zhang
Yi Ma
Yi Ma
Xiaopeng Zhang
author_sort Yuedong Wang
collection DOAJ
description To our knowledge, this is the first reported case of coexisting esophageal schwannoma and gastric fundus gastrointestinal stromal tumor (GIST). This case report describes the diagnostic and treatment process of a patient with esophageal schwannoma who also had a concurrent gastric fundus GIST and was presented to Hebei General Hospital (Hebei, China) in October 2024. The association between the pathogenesis of the two types of submucosal gastrointestinal tumors is unclear, with limited existing evidence in the literature. The esophageal schwannoma was misdiagnosed as a leiomyoma preoperatively, which prompted us to seek new diagnostic modalities to differentiate gastrointestinal submucosal lesions (leiomyomas, GISTs, and schwannomas). Surgical resection is considered the optimal treatment for esophageal schwannoma. The patient underwent a right single-port thoracoscopic esophageal tumor resection and recovered well, subsequently being discharged smoothly from the hospital.
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issn 2234-943X
language English
publishDate 2025-04-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Oncology
spelling doaj-art-aff441cc37a44325b6ac0c01467526a22025-08-20T02:11:41ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-04-011510.3389/fonc.2025.15734361573436Case Report: Coexistence of an esophageal schwannoma disguised as a leiomyoma with a gastrointestinal stromal tumor of the gastric fundusYuedong Wang0Yuedong Wang1Zhifei Xin2Wenbo Wu3Zhonghui Hu4Zhenghao Jia5Zhenghao Jia6Chengyao Zhang7Chengyao Zhang8Yi Ma9Yi Ma10Xiaopeng Zhang11Hebei Medical University, Shijiazhuang, Hebei, ChinaDepartment of Thoracic Surgery Hebei General Hospital, Shijiazhuang, Hebei, ChinaDepartment of Thoracic Surgery Hebei General Hospital, Shijiazhuang, Hebei, ChinaDepartment of Thoracic Surgery Hebei General Hospital, Shijiazhuang, Hebei, ChinaDepartment of Thoracic Surgery Hebei General Hospital, Shijiazhuang, Hebei, ChinaHebei Medical University, Shijiazhuang, Hebei, ChinaDepartment of Thoracic Surgery Hebei General Hospital, Shijiazhuang, Hebei, ChinaDepartment of Thoracic Surgery Hebei General Hospital, Shijiazhuang, Hebei, ChinaNorth China University of Science and Technology, Tangshan, Hebei, ChinaDepartment of Thoracic Surgery Hebei General Hospital, Shijiazhuang, Hebei, ChinaNorth China University of Science and Technology, Tangshan, Hebei, ChinaDepartment of Thoracic Surgery Hebei General Hospital, Shijiazhuang, Hebei, ChinaTo our knowledge, this is the first reported case of coexisting esophageal schwannoma and gastric fundus gastrointestinal stromal tumor (GIST). This case report describes the diagnostic and treatment process of a patient with esophageal schwannoma who also had a concurrent gastric fundus GIST and was presented to Hebei General Hospital (Hebei, China) in October 2024. The association between the pathogenesis of the two types of submucosal gastrointestinal tumors is unclear, with limited existing evidence in the literature. The esophageal schwannoma was misdiagnosed as a leiomyoma preoperatively, which prompted us to seek new diagnostic modalities to differentiate gastrointestinal submucosal lesions (leiomyomas, GISTs, and schwannomas). Surgical resection is considered the optimal treatment for esophageal schwannoma. The patient underwent a right single-port thoracoscopic esophageal tumor resection and recovered well, subsequently being discharged smoothly from the hospital.https://www.frontiersin.org/articles/10.3389/fonc.2025.1573436/fullesophageal schwannomaleiomyomagastrointestinal stromal tumorcase reportdifferential diagnosis
spellingShingle Yuedong Wang
Yuedong Wang
Zhifei Xin
Wenbo Wu
Zhonghui Hu
Zhenghao Jia
Zhenghao Jia
Chengyao Zhang
Chengyao Zhang
Yi Ma
Yi Ma
Xiaopeng Zhang
Case Report: Coexistence of an esophageal schwannoma disguised as a leiomyoma with a gastrointestinal stromal tumor of the gastric fundus
Frontiers in Oncology
esophageal schwannoma
leiomyoma
gastrointestinal stromal tumor
case report
differential diagnosis
title Case Report: Coexistence of an esophageal schwannoma disguised as a leiomyoma with a gastrointestinal stromal tumor of the gastric fundus
title_full Case Report: Coexistence of an esophageal schwannoma disguised as a leiomyoma with a gastrointestinal stromal tumor of the gastric fundus
title_fullStr Case Report: Coexistence of an esophageal schwannoma disguised as a leiomyoma with a gastrointestinal stromal tumor of the gastric fundus
title_full_unstemmed Case Report: Coexistence of an esophageal schwannoma disguised as a leiomyoma with a gastrointestinal stromal tumor of the gastric fundus
title_short Case Report: Coexistence of an esophageal schwannoma disguised as a leiomyoma with a gastrointestinal stromal tumor of the gastric fundus
title_sort case report coexistence of an esophageal schwannoma disguised as a leiomyoma with a gastrointestinal stromal tumor of the gastric fundus
topic esophageal schwannoma
leiomyoma
gastrointestinal stromal tumor
case report
differential diagnosis
url https://www.frontiersin.org/articles/10.3389/fonc.2025.1573436/full
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