The critical role of BMP signaling in gastric epithelial cell differentiation revealed by organoids

The critical role of BMP signaling in gastric epithelial cell differentiation revealed by organoids

Abstract The efficient differentiation of adult gastric stem cells into specific epithelial cell types is crucial for gastric homeostasis. Although it is well appreciated that the niche plays a critical role in gastric epithelium cell differentiation, the relevant molecular factors and the underlyin...

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Main Authors: Fan Hong, Xiaodan Wang, Nanshan Zhong, Ze Zhang, Shibo Lin, Mengxian Zhang, Haonan Li, Yuan Liu, Yalong Wang, Lianzheng Zhao, Xiao Yang, Hongwen Zhou, Hui Liang, Ye-Guang Chen
Format: Article
Language:English
Published: SpringerOpen 2025-05-01
Series:Cell Regeneration
Subjects:
Niche factors
Gastric epithelium
Cell differentiation
Organoids
Single cell RNA-seq
Online Access:https://doi.org/10.1186/s13619-025-00237-x
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