EVALUATION OF THE CHARACTERISTICS AND CLINICAL RESULTS OF THE PATIENTS HOSPITALIZED WITH COVID-19 PNEUMONIA IN THE PROVINCE OF MUS: A STATE HOSPITAL EXPERIENCE
Objective: In this study, we aimed to determine the characteristics of COVID-19 pneumonia patients, and also predict factors affecting the severity of the disease. Methods: This is a retrospective, single-center study. Hospitalized COVID-19 pneumonia patients aged over 18 years between March 19th 20...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Istanbul University Press
2021-04-01
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| Series: | İstanbul Tıp Fakültesi Dergisi |
| Subjects: | |
| Online Access: | https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/563D68AB81404181B46B8B54229A2E3D |
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| Summary: | Objective: In this study, we aimed to determine the characteristics of COVID-19 pneumonia patients, and also predict factors affecting the severity of the disease. Methods: This is a retrospective, single-center study. Hospitalized COVID-19 pneumonia patients aged over 18 years between March 19th 2020, and May 19th 2020 were included in the study. The demographic, and clinical characteristics of patients, and factors associated with severe COVID-19 were analyzed. Multivariate logistic regression analysis was performed to evaluate the factors predicting the severity of COVID-19. Results: A total of 228 patients with COVID-19 pneumonia were recorded. The mean age of the patients was 51±19 years, and 136 (59.6%) were men. Of the patients, 47.4% had at least one comorbidity. Intensive care unit (ICU) admission, and mortality were detected in 29 (12.7%), and in 17 (7.5%) patients respectively. No mortality was detected in non-severe disease. Our results revealed that dyspnea (OR:7.449 95% CI 2.444-22.708, p<0.001), fatigue (OR:5.968 96% CI 2.155-16.526, p:0.001), elevation of LDH (OR: 4.288 95% CI 1.109-16.584, p:0.035) and elevation of D-dimer (OR:3.242 95% CI 1.106-9.501, p:0.032) levels at admission were major independent predicting factors for severe COVID-19 disease. Conclusion: Dyspnea, fatigue, elevation of LDH and D-dimer levels are closely related to severe disease in COVID-19. In addition to typical pneumonia signs, fatigue, LDH, and D-dimer can be used as valuable indicators at admission for distinguishing severe COVID-19 pneumonia patients in the early stage. Therefore, this may lead to improved outcomes in patients hospitalized with COVID-19. |
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| ISSN: | 1305-6441 |