Demethylase FTO mediates m6A modification of ENST00000619282 to promote apoptosis escape in rheumatoid arthritis and the intervention effect of Xinfeng Capsule

Demethylase FTO mediates m6A modification of ENST00000619282 to promote apoptosis escape in rheumatoid arthritis and the intervention effect of Xinfeng Capsule

IntroductionThe pathological mechanisms of rheumatoid arthritis (RA) are closely associated with the apoptosis escape of fibroblast-like synoviocytes (FLS). The m6A modification of long non-coding RNAs (lncRNAs) plays a critical regulatory role in RA pathogenesis. Xinfeng Capsule (XFC), a clinically...

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Bibliographic Details
Main Authors: Fanfan Wang, Jianting Wen, Jian Liu, Ling Xin, Yanyan Fang, Yue Sun, Mingyu He
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Immunology
Subjects:
rheumatoid arthritis
Xinfeng Capsule
apoptosis escape
M6A
FTO
ENST00000619282
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1556764/full
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