Etiopathogenesis, diagnostic evaluation, and management of ovarian tuberculosis: A systematic review

Ovarian tuberculosis is a rare entity with non-specific clinical manifestations, difficult diagnosis, and specific medical management. Ovarian involvement in tuberculosis (TB) may occur in two forms, namely, perioophoritis and oophoritis. The constitutional symptoms of tuberculosis such as anorexia,...

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Main Authors: Ashutosh Nagpal, Poras Chaudhary
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
Online Access:https://journals.lww.com/10.4103/ijpm.ijpm_6_23
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author Ashutosh Nagpal
Poras Chaudhary
author_facet Ashutosh Nagpal
Poras Chaudhary
author_sort Ashutosh Nagpal
collection DOAJ
description Ovarian tuberculosis is a rare entity with non-specific clinical manifestations, difficult diagnosis, and specific medical management. Ovarian involvement in tuberculosis (TB) may occur in two forms, namely, perioophoritis and oophoritis. The constitutional symptoms of tuberculosis such as anorexia, weight loss, night sweats, and evening rise in temperature have been reported in up to 45% of patients. Misdiagnosis and delayed diagnosis are common. A direct histopathological demonstration is the best diagnostic modality. Fine needle aspiration cytology (FNAC) is the study of choice and polymerase chain reaction (PCR) assay increases its sensitivity. The standard short-course antituberculous for 6 months is recommended for isolated ovarian tuberculosis and for widespread disease, 12 months of therapy is recommended. Surgery is reserved for failure of medical therapy and abscess formation. There are many studies on genito-urinary tuberculosis but a detailed study defining diagnostic studies and management guidelines is still lacking. This article aims to present and share a review of the English-language literature on ovarian tuberculosis to gain a better understanding of etiopathogenesis and diagnostic methods and to provide guidelines for its management.
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issn 0377-4929
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publisher Wolters Kluwer Medknow Publications
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spelling doaj-art-afd5abaf485f4650a5ae29e9b21d59362025-01-22T15:07:23ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302023-01-016712910.4103/ijpm.ijpm_6_23Etiopathogenesis, diagnostic evaluation, and management of ovarian tuberculosis: A systematic reviewAshutosh NagpalPoras ChaudharyOvarian tuberculosis is a rare entity with non-specific clinical manifestations, difficult diagnosis, and specific medical management. Ovarian involvement in tuberculosis (TB) may occur in two forms, namely, perioophoritis and oophoritis. The constitutional symptoms of tuberculosis such as anorexia, weight loss, night sweats, and evening rise in temperature have been reported in up to 45% of patients. Misdiagnosis and delayed diagnosis are common. A direct histopathological demonstration is the best diagnostic modality. Fine needle aspiration cytology (FNAC) is the study of choice and polymerase chain reaction (PCR) assay increases its sensitivity. The standard short-course antituberculous for 6 months is recommended for isolated ovarian tuberculosis and for widespread disease, 12 months of therapy is recommended. Surgery is reserved for failure of medical therapy and abscess formation. There are many studies on genito-urinary tuberculosis but a detailed study defining diagnostic studies and management guidelines is still lacking. This article aims to present and share a review of the English-language literature on ovarian tuberculosis to gain a better understanding of etiopathogenesis and diagnostic methods and to provide guidelines for its management.https://journals.lww.com/10.4103/ijpm.ijpm_6_23biopsyetiopathogenesismedical managementovarian tuberculosissurgery
spellingShingle Ashutosh Nagpal
Poras Chaudhary
Etiopathogenesis, diagnostic evaluation, and management of ovarian tuberculosis: A systematic review
Indian Journal of Pathology and Microbiology
biopsy
etiopathogenesis
medical management
ovarian tuberculosis
surgery
title Etiopathogenesis, diagnostic evaluation, and management of ovarian tuberculosis: A systematic review
title_full Etiopathogenesis, diagnostic evaluation, and management of ovarian tuberculosis: A systematic review
title_fullStr Etiopathogenesis, diagnostic evaluation, and management of ovarian tuberculosis: A systematic review
title_full_unstemmed Etiopathogenesis, diagnostic evaluation, and management of ovarian tuberculosis: A systematic review
title_short Etiopathogenesis, diagnostic evaluation, and management of ovarian tuberculosis: A systematic review
title_sort etiopathogenesis diagnostic evaluation and management of ovarian tuberculosis a systematic review
topic biopsy
etiopathogenesis
medical management
ovarian tuberculosis
surgery
url https://journals.lww.com/10.4103/ijpm.ijpm_6_23
work_keys_str_mv AT ashutoshnagpal etiopathogenesisdiagnosticevaluationandmanagementofovariantuberculosisasystematicreview
AT poraschaudhary etiopathogenesisdiagnosticevaluationandmanagementofovariantuberculosisasystematicreview