Evaluating the Effects of Moringa Oleifera Leaf Extract on Testosterone Level of Male Wistar Rats Exposed to Petrol, Diesel and Kerosene
Testes are primary organ of reproduction as they are responsible for the production and release of testosterone. Testosterone is the major androgenic steroid hormone produced primarily in the Leydig cells, it has both intratesticular and peripheral effects. Petroleum products are mixtures derived fr...
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| Format: | Article |
| Language: | English |
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Hammer Head Production Limited
2024-03-01
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| Series: | Sokoto Journal of Medical Laboratory Science |
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| Online Access: | https://sokjmls.com.ng/index.php/SJMLS/article/view/460 |
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| author | Bashir Saidu', Ashiru Dahiru', Aliyu Jibril’, Ahmad Musa Dunfawa', Nafisat Abdulazeez' and Muawiyyah Muhammad Mahuta’ |
| author_facet | Bashir Saidu', Ashiru Dahiru', Aliyu Jibril’, Ahmad Musa Dunfawa', Nafisat Abdulazeez' and Muawiyyah Muhammad Mahuta’ |
| author_sort | Bashir Saidu', Ashiru Dahiru', Aliyu Jibril’, Ahmad Musa Dunfawa', Nafisat Abdulazeez' and Muawiyyah Muhammad Mahuta’ |
| collection | DOAJ |
| description | Testes are primary organ of reproduction as they are responsible for the production and release of testosterone. Testosterone is the major androgenic steroid hormone produced primarily in the Leydig cells, it has both intratesticular and peripheral effects. Petroleum products are mixtures derived from crude oil and have similar chemical and physical properties. Exposure to petroleum product fumes has been reported to have both an effect on global warming and reproductive diseases. Infertility, low sperm count and decreased sperm viability that is affecting reproductive performance among individuals might be due to changes in testosterone level as a result of exposure to petroleum products. The aim of this study was to investigate the effect of Moringa oleifera leaf extract on testosterone levels of male Wistar rats exposed to Petrol, Diesel, and Kerosene. An experimental study was conducted with a total of Twenty-one (21) adults male Wistar rats randomly divided into seven (7) groups comprising three rats each. 40mg/kg/rat of moringa extract and 0.008 cm3/min/rat exposure dose were used in this study. The result showed an increase in serum testosterone level in the exposed groups and treatments with moringa oleifera leaf extract has shown a promising effect. Inconclusion, the result of this study shows that exposure of Wistar rats to petroleum products through inhalation, causes marked increase in serum testosterone levels and treatment with Moringa oleifera leafextract showed promising result. |
| format | Article |
| id | doaj-art-afd24d2e8b464969b0f945b4612dc0a0 |
| institution | DOAJ |
| issn | 2536-7153 |
| language | English |
| publishDate | 2024-03-01 |
| publisher | Hammer Head Production Limited |
| record_format | Article |
| series | Sokoto Journal of Medical Laboratory Science |
| spelling | doaj-art-afd24d2e8b464969b0f945b4612dc0a02025-08-20T02:51:42ZengHammer Head Production LimitedSokoto Journal of Medical Laboratory Science2536-71532024-03-0191460Evaluating the Effects of Moringa Oleifera Leaf Extract on Testosterone Level of Male Wistar Rats Exposed to Petrol, Diesel and KeroseneBashir Saidu', Ashiru Dahiru', Aliyu Jibril’, Ahmad Musa Dunfawa', Nafisat Abdulazeez' and Muawiyyah Muhammad Mahuta’Testes are primary organ of reproduction as they are responsible for the production and release of testosterone. Testosterone is the major androgenic steroid hormone produced primarily in the Leydig cells, it has both intratesticular and peripheral effects. Petroleum products are mixtures derived from crude oil and have similar chemical and physical properties. Exposure to petroleum product fumes has been reported to have both an effect on global warming and reproductive diseases. Infertility, low sperm count and decreased sperm viability that is affecting reproductive performance among individuals might be due to changes in testosterone level as a result of exposure to petroleum products. The aim of this study was to investigate the effect of Moringa oleifera leaf extract on testosterone levels of male Wistar rats exposed to Petrol, Diesel, and Kerosene. An experimental study was conducted with a total of Twenty-one (21) adults male Wistar rats randomly divided into seven (7) groups comprising three rats each. 40mg/kg/rat of moringa extract and 0.008 cm3/min/rat exposure dose were used in this study. The result showed an increase in serum testosterone level in the exposed groups and treatments with moringa oleifera leaf extract has shown a promising effect. Inconclusion, the result of this study shows that exposure of Wistar rats to petroleum products through inhalation, causes marked increase in serum testosterone levels and treatment with Moringa oleifera leafextract showed promising result.https://sokjmls.com.ng/index.php/SJMLS/article/view/460wistar rat, moringa oleifera, petrol, |
| spellingShingle | Bashir Saidu', Ashiru Dahiru', Aliyu Jibril’, Ahmad Musa Dunfawa', Nafisat Abdulazeez' and Muawiyyah Muhammad Mahuta’ Evaluating the Effects of Moringa Oleifera Leaf Extract on Testosterone Level of Male Wistar Rats Exposed to Petrol, Diesel and Kerosene Sokoto Journal of Medical Laboratory Science wistar rat, moringa oleifera, petrol, |
| title | Evaluating the Effects of Moringa Oleifera Leaf Extract on Testosterone Level of Male Wistar Rats Exposed to Petrol, Diesel and Kerosene |
| title_full | Evaluating the Effects of Moringa Oleifera Leaf Extract on Testosterone Level of Male Wistar Rats Exposed to Petrol, Diesel and Kerosene |
| title_fullStr | Evaluating the Effects of Moringa Oleifera Leaf Extract on Testosterone Level of Male Wistar Rats Exposed to Petrol, Diesel and Kerosene |
| title_full_unstemmed | Evaluating the Effects of Moringa Oleifera Leaf Extract on Testosterone Level of Male Wistar Rats Exposed to Petrol, Diesel and Kerosene |
| title_short | Evaluating the Effects of Moringa Oleifera Leaf Extract on Testosterone Level of Male Wistar Rats Exposed to Petrol, Diesel and Kerosene |
| title_sort | evaluating the effects of moringa oleifera leaf extract on testosterone level of male wistar rats exposed to petrol diesel and kerosene |
| topic | wistar rat, moringa oleifera, petrol, |
| url | https://sokjmls.com.ng/index.php/SJMLS/article/view/460 |
| work_keys_str_mv | AT bashirsaiduashirudahirualiyujibrilahmadmusadunfawanafisatabdulazeezandmuawiyyahmuhammadmahuta evaluatingtheeffectsofmoringaoleiferaleafextractontestosteronelevelofmalewistarratsexposedtopetroldieselandkerosene |