Prediction Models for Perioperative Blood Transfusion in Patients Undergoing Gynecologic Surgery: A Systematic Review

This systematic review aimed to evaluate prediction models for perioperative blood transfusion in patients undergoing gynecologic surgery. Given the inherent risks associated with blood transfusion and the critical need for accurate prediction, this study identified and assessed models based on thei...

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Main Authors: Zhongmian Pan, Kittipat Charoenkwan
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/14/18/2018
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author Zhongmian Pan
Kittipat Charoenkwan
author_facet Zhongmian Pan
Kittipat Charoenkwan
author_sort Zhongmian Pan
collection DOAJ
description This systematic review aimed to evaluate prediction models for perioperative blood transfusion in patients undergoing gynecologic surgery. Given the inherent risks associated with blood transfusion and the critical need for accurate prediction, this study identified and assessed models based on their development, validation, and predictive performance. The review included five studies encompassing various surgical procedures and approaches. Predicting factors commonly used across these models included preoperative hematocrit, race, surgical route, and uterine fibroid characteristics. However, the review highlighted significant variability in the definition of perioperative periods, a lack of standardization in transfusion criteria, and a high risk of bias in most models due to methodological issues, such as a low number of events per variable, inappropriate handling of continuous and categorical predictors, inappropriate handling of missing data, improper methods of predictor selection, inappropriate measurement methods for model performance, and inadequate evaluations of model overfitting and optimism in model performance. Despite some models demonstrating good discrimination and calibration, the overall quality and external validation of these models were limited. Consequently, there is a clear need for more robust and externally validated models to improve clinical decision-making and patient outcomes in gynecologic surgery. Future research should focus on refining these models, incorporating rigorous validation, and adhering to standardized reporting practices.
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spelling doaj-art-afc81b1f9230426cb81d4a394b37ffd22025-08-20T01:55:30ZengMDPI AGDiagnostics2075-44182024-09-011418201810.3390/diagnostics14182018Prediction Models for Perioperative Blood Transfusion in Patients Undergoing Gynecologic Surgery: A Systematic ReviewZhongmian Pan0Kittipat Charoenkwan1Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandDepartment of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandThis systematic review aimed to evaluate prediction models for perioperative blood transfusion in patients undergoing gynecologic surgery. Given the inherent risks associated with blood transfusion and the critical need for accurate prediction, this study identified and assessed models based on their development, validation, and predictive performance. The review included five studies encompassing various surgical procedures and approaches. Predicting factors commonly used across these models included preoperative hematocrit, race, surgical route, and uterine fibroid characteristics. However, the review highlighted significant variability in the definition of perioperative periods, a lack of standardization in transfusion criteria, and a high risk of bias in most models due to methodological issues, such as a low number of events per variable, inappropriate handling of continuous and categorical predictors, inappropriate handling of missing data, improper methods of predictor selection, inappropriate measurement methods for model performance, and inadequate evaluations of model overfitting and optimism in model performance. Despite some models demonstrating good discrimination and calibration, the overall quality and external validation of these models were limited. Consequently, there is a clear need for more robust and externally validated models to improve clinical decision-making and patient outcomes in gynecologic surgery. Future research should focus on refining these models, incorporating rigorous validation, and adhering to standardized reporting practices.https://www.mdpi.com/2075-4418/14/18/2018blood lossblood transfusiongynecologic surgeryprediction modelsystematic review
spellingShingle Zhongmian Pan
Kittipat Charoenkwan
Prediction Models for Perioperative Blood Transfusion in Patients Undergoing Gynecologic Surgery: A Systematic Review
Diagnostics
blood loss
blood transfusion
gynecologic surgery
prediction model
systematic review
title Prediction Models for Perioperative Blood Transfusion in Patients Undergoing Gynecologic Surgery: A Systematic Review
title_full Prediction Models for Perioperative Blood Transfusion in Patients Undergoing Gynecologic Surgery: A Systematic Review
title_fullStr Prediction Models for Perioperative Blood Transfusion in Patients Undergoing Gynecologic Surgery: A Systematic Review
title_full_unstemmed Prediction Models for Perioperative Blood Transfusion in Patients Undergoing Gynecologic Surgery: A Systematic Review
title_short Prediction Models for Perioperative Blood Transfusion in Patients Undergoing Gynecologic Surgery: A Systematic Review
title_sort prediction models for perioperative blood transfusion in patients undergoing gynecologic surgery a systematic review
topic blood loss
blood transfusion
gynecologic surgery
prediction model
systematic review
url https://www.mdpi.com/2075-4418/14/18/2018
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