Transformation of Synthetic Allicin: The Influence of Ultrasound, Microwaves, Different Solvents and Temperatures, and the Products Isolation
The transformation of the synthesized allicin, using conventional method, the influence of ultrasound and microwaves, in different organic solvents (acetonitrile, acetone, methanol, and chloroform), at various temperatures (room temperature, 45∘C, and 55∘C) was investigated. Allicin degradation kine...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/2012/561823 |
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| author | Dušica Ilić Vesna Nikolić Mihajlo Stanković Ljubiša Nikolić Ljiljana Stanojević Ivana Mladenović-Ranisavljević Andrija Šmelcerović |
| author_facet | Dušica Ilić Vesna Nikolić Mihajlo Stanković Ljubiša Nikolić Ljiljana Stanojević Ivana Mladenović-Ranisavljević Andrija Šmelcerović |
| author_sort | Dušica Ilić |
| collection | DOAJ |
| description | The transformation of the synthesized allicin, using conventional method, the influence of ultrasound and microwaves, in different organic solvents (acetonitrile, acetone, methanol, and chloroform), at various temperatures (room temperature, 45∘C, and 55∘C) was investigated. Allicin degradation kinetic was monitored by HPLC. Allicin transformation under the effect of microwaves is faster than transformations performed under the influence of ultrasound or by conventional method. Increase of the temperature accelerates allicin transformation. Pharmacologically active compounds of (E)-ajoene, (Z)-ajoene, 3-vinyl-4H-1,2-dithiin, 2-vinyl-4H-1,3-dithiin, and diallyl disulfide were isolated from the mixture of transformation products of allicin under the influence of microwaves in methanol at 55∘C, which is according to kinetic parameters (highest values of the order of reaction and the lowest activation energy) the optimal method. |
| format | Article |
| id | doaj-art-afbdecc22d60467fb8a30b20cd156e6b |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-afbdecc22d60467fb8a30b20cd156e6b2025-08-20T03:39:05ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/561823561823Transformation of Synthetic Allicin: The Influence of Ultrasound, Microwaves, Different Solvents and Temperatures, and the Products IsolationDušica Ilić0Vesna Nikolić1Mihajlo Stanković2Ljubiša Nikolić3Ljiljana Stanojević4Ivana Mladenović-Ranisavljević5Andrija Šmelcerović6Faculty of Technology, University of Niš, Leskovac, SerbiaFaculty of Technology, University of Niš, Leskovac, SerbiaFaculty of Technology, University of Niš, Leskovac, SerbiaFaculty of Technology, University of Niš, Leskovac, SerbiaFaculty of Technology, University of Niš, Leskovac, SerbiaFaculty of Technology, University of Niš, Leskovac, SerbiaDepartment of Pharmacy, Faculty of Medicine, University of Niš, Niš, SerbiaThe transformation of the synthesized allicin, using conventional method, the influence of ultrasound and microwaves, in different organic solvents (acetonitrile, acetone, methanol, and chloroform), at various temperatures (room temperature, 45∘C, and 55∘C) was investigated. Allicin degradation kinetic was monitored by HPLC. Allicin transformation under the effect of microwaves is faster than transformations performed under the influence of ultrasound or by conventional method. Increase of the temperature accelerates allicin transformation. Pharmacologically active compounds of (E)-ajoene, (Z)-ajoene, 3-vinyl-4H-1,2-dithiin, 2-vinyl-4H-1,3-dithiin, and diallyl disulfide were isolated from the mixture of transformation products of allicin under the influence of microwaves in methanol at 55∘C, which is according to kinetic parameters (highest values of the order of reaction and the lowest activation energy) the optimal method.http://dx.doi.org/10.1100/2012/561823 |
| spellingShingle | Dušica Ilić Vesna Nikolić Mihajlo Stanković Ljubiša Nikolić Ljiljana Stanojević Ivana Mladenović-Ranisavljević Andrija Šmelcerović Transformation of Synthetic Allicin: The Influence of Ultrasound, Microwaves, Different Solvents and Temperatures, and the Products Isolation The Scientific World Journal |
| title | Transformation of Synthetic Allicin: The Influence of Ultrasound, Microwaves, Different Solvents and Temperatures, and the Products Isolation |
| title_full | Transformation of Synthetic Allicin: The Influence of Ultrasound, Microwaves, Different Solvents and Temperatures, and the Products Isolation |
| title_fullStr | Transformation of Synthetic Allicin: The Influence of Ultrasound, Microwaves, Different Solvents and Temperatures, and the Products Isolation |
| title_full_unstemmed | Transformation of Synthetic Allicin: The Influence of Ultrasound, Microwaves, Different Solvents and Temperatures, and the Products Isolation |
| title_short | Transformation of Synthetic Allicin: The Influence of Ultrasound, Microwaves, Different Solvents and Temperatures, and the Products Isolation |
| title_sort | transformation of synthetic allicin the influence of ultrasound microwaves different solvents and temperatures and the products isolation |
| url | http://dx.doi.org/10.1100/2012/561823 |
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