Correlation of Ultrasonographic Findings in Renal Parenchymal Disease with Creatinine Levels at a Tertiary Care Setting in Rawalpindi

Objective: The study aims to determine the correlation of ultrasonic measurements in assessing renal parenchymal disease (RPD) with the results of creatinine levels in serum to support or oppose the findings. Study Design: Cross-sectional and descriptive study. Place and Duration of Study: This stud...

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Main Authors: Laiba Zahid, Muhammad Zeeshan Ali, Sarah Ali Khan, Nisar Ahmed, Aneela Akram, Fazeela Ibrahim
Format: Article
Language:English
Published: National University of Medical Sciences 2025-01-01
Series:Life and Science
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Online Access:https://ojs.lifenscience.org/index.php/life-and-science/article/view/694
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author Laiba Zahid
Muhammad Zeeshan Ali
Sarah Ali Khan
Nisar Ahmed
Aneela Akram
Fazeela Ibrahim
author_facet Laiba Zahid
Muhammad Zeeshan Ali
Sarah Ali Khan
Nisar Ahmed
Aneela Akram
Fazeela Ibrahim
author_sort Laiba Zahid
collection DOAJ
description Objective: The study aims to determine the correlation of ultrasonic measurements in assessing renal parenchymal disease (RPD) with the results of creatinine levels in serum to support or oppose the findings. Study Design: Cross-sectional and descriptive study. Place and Duration of Study: This study was conducted at the Department of Radiology, Armed Forces Institute of Radiology and Imaging (AFIRI) Rawalpindi, Pakistan, from September 2022 to February 2023. Methods: Two diagnostic tools were used, i.e., ultrasound and serum creatinine levels. All the patients reporting at a tertiary care hospital for Abdomen and Kidney Ureter Bladder (KUB) ultrasound were included.  All the results were finalized under the supervision of a Classified Radiologist. Those patients who hadn’t had their serum creatinine levels checked beforehand were asked to get it done and provide the results later on. The data was analyzed using the Statistical Package for Social Sciences (SPSS) version 26. Pearson’s correlation was done to find the relationship of serum creatinine with different ultrasound parameters. Results: A positive correlation that was statistically significant was found to exist between serum creatinine and echogenicity grades (r = 0.418, P < 0.0001), renal length (r = 0.220, P < 0.0001), corticomedullary differentiation (r = 0.354, P < 0.0001) and parenchymal echogenicity (r = 0.261, P <0.001) in right kidney. Similarly, in the left kidney, a significant positive relationship that was confirmed through statistical analysis was found between serum creatinine and echogenicity grades (r = 0.435, P <0.0001), renal length (r = 0.169, P = 0.003), corticomedullary differentiation (r = 0.338, P < 0.0001) and parenchymal echogenicity (r = 0.294, P <0.001).  Conclusion: The results produced a significant correlation through statistical analysis between sonographic findings and serum creatinine levels paving the way for the use of ultrasonography as an early diagnostic tool for the timely diagnosis of renal parenchymal disease. How to cite this: Zahid L, Ali MZ, Khan SA, Ahmed N, Akram A, Ibrahim F. Correlation of Ultrasonographic Findings in Renal Parenchymal Disease with Creatinine Levels at a Tertiary Care Setting in Rawalpindi. Life and Science. 2025; 6(1): 58-64. doi: http://doi.org/10.37185/LnS.1.1.694
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spelling doaj-art-afb6372e9b074c33a19b3f9cfd6999bc2025-08-20T03:43:54ZengNational University of Medical SciencesLife and Science2521-04752708-29702025-01-0161070710.37185/LnS.1.1.694694Correlation of Ultrasonographic Findings in Renal Parenchymal Disease with Creatinine Levels at a Tertiary Care Setting in RawalpindiLaiba Zahid0Muhammad Zeeshan Ali1Sarah Ali Khan2Nisar Ahmed3Aneela Akram4Fazeela Ibrahim5Armed Forces Institute of Radiology & Imaging (AFIRI) Rawalpindi, PakistanArmed Forces Institute of Radiology & Imaging (AFIRI) Rawalpindi, PakistanArmed Forces Institute of Radiology & Imaging (AFIRI) Rawalpindi, PakistanArmed Forces Institute of Radiology & Imaging (AFIRI) Rawalpindi, PakistanArmed Forces Institute of Radiology & Imaging (AFIRI) Rawalpindi, PakistanArmed Forces Institute of Radiology & Imaging (AFIRI) Rawalpindi, PakistanObjective: The study aims to determine the correlation of ultrasonic measurements in assessing renal parenchymal disease (RPD) with the results of creatinine levels in serum to support or oppose the findings. Study Design: Cross-sectional and descriptive study. Place and Duration of Study: This study was conducted at the Department of Radiology, Armed Forces Institute of Radiology and Imaging (AFIRI) Rawalpindi, Pakistan, from September 2022 to February 2023. Methods: Two diagnostic tools were used, i.e., ultrasound and serum creatinine levels. All the patients reporting at a tertiary care hospital for Abdomen and Kidney Ureter Bladder (KUB) ultrasound were included.  All the results were finalized under the supervision of a Classified Radiologist. Those patients who hadn’t had their serum creatinine levels checked beforehand were asked to get it done and provide the results later on. The data was analyzed using the Statistical Package for Social Sciences (SPSS) version 26. Pearson’s correlation was done to find the relationship of serum creatinine with different ultrasound parameters. Results: A positive correlation that was statistically significant was found to exist between serum creatinine and echogenicity grades (r = 0.418, P < 0.0001), renal length (r = 0.220, P < 0.0001), corticomedullary differentiation (r = 0.354, P < 0.0001) and parenchymal echogenicity (r = 0.261, P <0.001) in right kidney. Similarly, in the left kidney, a significant positive relationship that was confirmed through statistical analysis was found between serum creatinine and echogenicity grades (r = 0.435, P <0.0001), renal length (r = 0.169, P = 0.003), corticomedullary differentiation (r = 0.338, P < 0.0001) and parenchymal echogenicity (r = 0.294, P <0.001).  Conclusion: The results produced a significant correlation through statistical analysis between sonographic findings and serum creatinine levels paving the way for the use of ultrasonography as an early diagnostic tool for the timely diagnosis of renal parenchymal disease. How to cite this: Zahid L, Ali MZ, Khan SA, Ahmed N, Akram A, Ibrahim F. Correlation of Ultrasonographic Findings in Renal Parenchymal Disease with Creatinine Levels at a Tertiary Care Setting in Rawalpindi. Life and Science. 2025; 6(1): 58-64. doi: http://doi.org/10.37185/LnS.1.1.694https://ojs.lifenscience.org/index.php/life-and-science/article/view/694acute kidney injurycreatininechronic kidney diseaseglomerular filtration rateultrasonography
spellingShingle Laiba Zahid
Muhammad Zeeshan Ali
Sarah Ali Khan
Nisar Ahmed
Aneela Akram
Fazeela Ibrahim
Correlation of Ultrasonographic Findings in Renal Parenchymal Disease with Creatinine Levels at a Tertiary Care Setting in Rawalpindi
Life and Science
acute kidney injury
creatinine
chronic kidney disease
glomerular filtration rate
ultrasonography
title Correlation of Ultrasonographic Findings in Renal Parenchymal Disease with Creatinine Levels at a Tertiary Care Setting in Rawalpindi
title_full Correlation of Ultrasonographic Findings in Renal Parenchymal Disease with Creatinine Levels at a Tertiary Care Setting in Rawalpindi
title_fullStr Correlation of Ultrasonographic Findings in Renal Parenchymal Disease with Creatinine Levels at a Tertiary Care Setting in Rawalpindi
title_full_unstemmed Correlation of Ultrasonographic Findings in Renal Parenchymal Disease with Creatinine Levels at a Tertiary Care Setting in Rawalpindi
title_short Correlation of Ultrasonographic Findings in Renal Parenchymal Disease with Creatinine Levels at a Tertiary Care Setting in Rawalpindi
title_sort correlation of ultrasonographic findings in renal parenchymal disease with creatinine levels at a tertiary care setting in rawalpindi
topic acute kidney injury
creatinine
chronic kidney disease
glomerular filtration rate
ultrasonography
url https://ojs.lifenscience.org/index.php/life-and-science/article/view/694
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