Dietary antioxidants and obesity: a new perspective on the role of composite dietary antioxidant index in reducing obesity risk using a dual-criteria definition
ObjectiveTo investigate the association between the Composite Dietary Antioxidant Index (CDAI) and obesity defined by both BMI and waist circumference (WC).MethodsThis was a cross-sectional study using data from the National Health and Nutrition Examination Survey (NHANES) 2009–2018. Multivariable l...
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| Language: | English |
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Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2025.1600925/full |
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| author | Yi-Qian Chen Chen Wang Yi-Jie Zhang Yue-Yang Zhang |
| author_facet | Yi-Qian Chen Chen Wang Yi-Jie Zhang Yue-Yang Zhang |
| author_sort | Yi-Qian Chen |
| collection | DOAJ |
| description | ObjectiveTo investigate the association between the Composite Dietary Antioxidant Index (CDAI) and obesity defined by both BMI and waist circumference (WC).MethodsThis was a cross-sectional study using data from the National Health and Nutrition Examination Survey (NHANES) 2009–2018. Multivariable logistic regression models and restricted cubic splines were used to assess the relationship between CDAI and obesity, defined as BMI ≥ 30 kg/m2 combined with WC ≥ 88 cm (women) or ≥102 cm (men). Models were adjusted for sociodemographic, lifestyle, and comorbidity factors. A stratified analysis and sensitivity analysis were also conducted.ResultsAmong 17,067 participants, CDAI was inversely associated with obesity (OR: 0.97, 95% CI: 0.95–0.99). Participants in the highest CDAI quartile had a 23% lower obesity risk compared to the lowest quartile (OR: 0.77, 95% CI: 0.62–0.95). Subgroup and sensitivity analyses yielded consistent results.ConclusionCDAI is inversely associated with obesity defined by dual criteria, suggesting that dietary antioxidants may play a protective role in obesity prevention. By using a more comprehensive definition of obesity, our study provides insights that are more directly applicable to clinical practice and public health strategies aimed at reducing obesity-related morbidity and mortality. |
| format | Article |
| id | doaj-art-afa485c587d34dc5bf10d6b890415aab |
| institution | DOAJ |
| issn | 2296-861X |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj-art-afa485c587d34dc5bf10d6b890415aab2025-08-20T03:09:34ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2025-07-011210.3389/fnut.2025.16009251600925Dietary antioxidants and obesity: a new perspective on the role of composite dietary antioxidant index in reducing obesity risk using a dual-criteria definitionYi-Qian ChenChen WangYi-Jie ZhangYue-Yang ZhangObjectiveTo investigate the association between the Composite Dietary Antioxidant Index (CDAI) and obesity defined by both BMI and waist circumference (WC).MethodsThis was a cross-sectional study using data from the National Health and Nutrition Examination Survey (NHANES) 2009–2018. Multivariable logistic regression models and restricted cubic splines were used to assess the relationship between CDAI and obesity, defined as BMI ≥ 30 kg/m2 combined with WC ≥ 88 cm (women) or ≥102 cm (men). Models were adjusted for sociodemographic, lifestyle, and comorbidity factors. A stratified analysis and sensitivity analysis were also conducted.ResultsAmong 17,067 participants, CDAI was inversely associated with obesity (OR: 0.97, 95% CI: 0.95–0.99). Participants in the highest CDAI quartile had a 23% lower obesity risk compared to the lowest quartile (OR: 0.77, 95% CI: 0.62–0.95). Subgroup and sensitivity analyses yielded consistent results.ConclusionCDAI is inversely associated with obesity defined by dual criteria, suggesting that dietary antioxidants may play a protective role in obesity prevention. By using a more comprehensive definition of obesity, our study provides insights that are more directly applicable to clinical practice and public health strategies aimed at reducing obesity-related morbidity and mortality.https://www.frontiersin.org/articles/10.3389/fnut.2025.1600925/fullcomposite dietary antioxidant indexobesityNHANESBMIwaist circumference |
| spellingShingle | Yi-Qian Chen Chen Wang Yi-Jie Zhang Yue-Yang Zhang Dietary antioxidants and obesity: a new perspective on the role of composite dietary antioxidant index in reducing obesity risk using a dual-criteria definition Frontiers in Nutrition composite dietary antioxidant index obesity NHANES BMI waist circumference |
| title | Dietary antioxidants and obesity: a new perspective on the role of composite dietary antioxidant index in reducing obesity risk using a dual-criteria definition |
| title_full | Dietary antioxidants and obesity: a new perspective on the role of composite dietary antioxidant index in reducing obesity risk using a dual-criteria definition |
| title_fullStr | Dietary antioxidants and obesity: a new perspective on the role of composite dietary antioxidant index in reducing obesity risk using a dual-criteria definition |
| title_full_unstemmed | Dietary antioxidants and obesity: a new perspective on the role of composite dietary antioxidant index in reducing obesity risk using a dual-criteria definition |
| title_short | Dietary antioxidants and obesity: a new perspective on the role of composite dietary antioxidant index in reducing obesity risk using a dual-criteria definition |
| title_sort | dietary antioxidants and obesity a new perspective on the role of composite dietary antioxidant index in reducing obesity risk using a dual criteria definition |
| topic | composite dietary antioxidant index obesity NHANES BMI waist circumference |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2025.1600925/full |
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