Hypoxia Associated Proteolytic Processing of OS-9 by the Metalloproteinase Meprin β

Meprin metalloproteases play a role in the pathology of ischemia/reperfusion- (IR-) induced renal injury. The endoplasmic reticulum-associated protein, osteosarcoma-9 (OS-9), has been shown to interact with the carboxyl-terminal tail of meprin β. More importantly, OS-9 interacts with the hypoxia ind...

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Bibliographic Details
Main Authors: Barry Lee Martin, Sabena Michelle Conley, Regine Simone Harris, Corshe Devon Stanley, Jean-Marie Vianney Niyitegeka, Elimelda Moige Ongeri
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:International Journal of Nephrology
Online Access:http://dx.doi.org/10.1155/2016/2851803
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