AKR1C2 silencing promotes ferroptosis and inhibits proliferation, migration, and invasion in lung cancer cells.

AKR1C2 silencing promotes ferroptosis and inhibits proliferation, migration, and invasion in lung cancer cells.

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<h4>Background</h4>Lung cancer is the leading cause of cancer-related deaths worldwide, so research and development of potential therapeutic targets is urgent.<h4>Methods</h4>The target gene, AKR1C2, was screened using the TCGA and FerrDb databases. The expression of AKR1C2 i...

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Bibliographic Details
Main Authors: Yi Cui, Zhihui Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0325995
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