Hemp Microbiome Composition and Function Under Developing Pest Management Solutions

Conventional pesticides used in cropping systems prevent damage caused by pathogens and pests but may also have unintended consequences for nontarget organisms associated with plants. For example, fungicide application may affect microbes such as fungal endophytes that potentially confer protective...

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Main Authors: Allison M. Rietman, Lucía Amani, Connor N. Morozumi, Nicole A. Gauthier, Natalie Christian
Format: Article
Language:English
Published: The American Phytopathological Society 2025-06-01
Series:Phytobiomes Journal
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Online Access:https://apsjournals.apsnet.org/doi/10.1094/PBIOMES-08-24-0077-R
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author Allison M. Rietman
Lucía Amani
Connor N. Morozumi
Nicole A. Gauthier
Natalie Christian
author_facet Allison M. Rietman
Lucía Amani
Connor N. Morozumi
Nicole A. Gauthier
Natalie Christian
author_sort Allison M. Rietman
collection DOAJ
description Conventional pesticides used in cropping systems prevent damage caused by pathogens and pests but may also have unintended consequences for nontarget organisms associated with plants. For example, fungicide application may affect microbes such as fungal endophytes that potentially confer protective benefits to the host, such as pathogen or pest resistance. Here, we investigated how fungicide application and pathogen inoculation altered the communities of pathogenic and nontarget endophytic leaf microbes in hemp (Cannabis sativa L.). We found that fungicide application and inoculation with fungal pathogens affected hemp-associated microbial communities. Fungicide application altered fungal endophyte community composition, increased the heterogeneity of fungal communities, reduced pathogen abundance, and decreased the diversity of the endophytic fungal community. Inoculation with pathogenic fungi decreased the abundance of bacterial endophytes relative to control and fungicide-treated plants. We then investigated the potential of a common fungal endophyte isolated from this study, Ophiocordyceps sp., as a biological control agent for Helicoverpa zea, a common insect pest in hemp. Contrary to our expectations, larvae preferred food inoculated with Ophiocordyceps sp., although it did not alter the growth or mortality of larvae. Together, our results indicate that hemp-associated endophyte communities are sensitive to abiotic and biotic manipulations and that fungicide application impacts nontarget microorganisms that could confer important functions for crop health. We encourage future studies to analyze the impact of biological control agents on host ecology in an integrated pest management plan and to examine ways to better utilize existing microbial associations to create biological controls. [Figure: see text] Copyright © 2025 The Author(s). This is an open access article distributed under the CC BY-NC-ND 4.0 International license.
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spelling doaj-art-af948767d14643dca84800e97ee2bd502025-08-20T03:09:51ZengThe American Phytopathological SocietyPhytobiomes Journal2471-29062025-06-019231732610.1094/PBIOMES-08-24-0077-RHemp Microbiome Composition and Function Under Developing Pest Management SolutionsAllison M. Rietman0Lucía Amani1Connor N. Morozumi2Nicole A. Gauthier3Natalie Christian4Department of Biology, University of Louisville, Louisville, KY 40292, U.S.A.Department of Biology, University of Louisville, Louisville, KY 40292, U.S.A.Department of Biology, University of Louisville, Louisville, KY 40292, U.S.A.Department of Plant Pathology, University of Kentucky, Lexington, KY 40546, U.S.A.Department of Biology, University of Louisville, Louisville, KY 40292, U.S.A.Conventional pesticides used in cropping systems prevent damage caused by pathogens and pests but may also have unintended consequences for nontarget organisms associated with plants. For example, fungicide application may affect microbes such as fungal endophytes that potentially confer protective benefits to the host, such as pathogen or pest resistance. Here, we investigated how fungicide application and pathogen inoculation altered the communities of pathogenic and nontarget endophytic leaf microbes in hemp (Cannabis sativa L.). We found that fungicide application and inoculation with fungal pathogens affected hemp-associated microbial communities. Fungicide application altered fungal endophyte community composition, increased the heterogeneity of fungal communities, reduced pathogen abundance, and decreased the diversity of the endophytic fungal community. Inoculation with pathogenic fungi decreased the abundance of bacterial endophytes relative to control and fungicide-treated plants. We then investigated the potential of a common fungal endophyte isolated from this study, Ophiocordyceps sp., as a biological control agent for Helicoverpa zea, a common insect pest in hemp. Contrary to our expectations, larvae preferred food inoculated with Ophiocordyceps sp., although it did not alter the growth or mortality of larvae. Together, our results indicate that hemp-associated endophyte communities are sensitive to abiotic and biotic manipulations and that fungicide application impacts nontarget microorganisms that could confer important functions for crop health. We encourage future studies to analyze the impact of biological control agents on host ecology in an integrated pest management plan and to examine ways to better utilize existing microbial associations to create biological controls. [Figure: see text] Copyright © 2025 The Author(s). This is an open access article distributed under the CC BY-NC-ND 4.0 International license.https://apsjournals.apsnet.org/doi/10.1094/PBIOMES-08-24-0077-RCannabis sativaintegrated pest managementleaf spot diseasemicrobiomeSeptoria
spellingShingle Allison M. Rietman
Lucía Amani
Connor N. Morozumi
Nicole A. Gauthier
Natalie Christian
Hemp Microbiome Composition and Function Under Developing Pest Management Solutions
Phytobiomes Journal
Cannabis sativa
integrated pest management
leaf spot disease
microbiome
Septoria
title Hemp Microbiome Composition and Function Under Developing Pest Management Solutions
title_full Hemp Microbiome Composition and Function Under Developing Pest Management Solutions
title_fullStr Hemp Microbiome Composition and Function Under Developing Pest Management Solutions
title_full_unstemmed Hemp Microbiome Composition and Function Under Developing Pest Management Solutions
title_short Hemp Microbiome Composition and Function Under Developing Pest Management Solutions
title_sort hemp microbiome composition and function under developing pest management solutions
topic Cannabis sativa
integrated pest management
leaf spot disease
microbiome
Septoria
url https://apsjournals.apsnet.org/doi/10.1094/PBIOMES-08-24-0077-R
work_keys_str_mv AT allisonmrietman hempmicrobiomecompositionandfunctionunderdevelopingpestmanagementsolutions
AT luciaamani hempmicrobiomecompositionandfunctionunderdevelopingpestmanagementsolutions
AT connornmorozumi hempmicrobiomecompositionandfunctionunderdevelopingpestmanagementsolutions
AT nicoleagauthier hempmicrobiomecompositionandfunctionunderdevelopingpestmanagementsolutions
AT nataliechristian hempmicrobiomecompositionandfunctionunderdevelopingpestmanagementsolutions