Impact of dietary protein hydrolysates on cognitive performance: A systematic review of randomized controlled trials involving adults
Changes in cerebral blood flow (CBF) - a marker of brain vascular function - may improve cognitive performance, and enhancing CBF through a healthy lifestyle could mitigate cognitive decline. Protein hydrolysates have shown potential to improve brain health. This systematic review analyzed randomize...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | Journal of Functional Foods |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464625000258 |
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| author | Micah S. Adams Ronald P. Mensink Peter J. Joris |
| author_facet | Micah S. Adams Ronald P. Mensink Peter J. Joris |
| author_sort | Micah S. Adams |
| collection | DOAJ |
| description | Changes in cerebral blood flow (CBF) - a marker of brain vascular function - may improve cognitive performance, and enhancing CBF through a healthy lifestyle could mitigate cognitive decline. Protein hydrolysates have shown potential to improve brain health. This systematic review analyzed randomized controlled trials on the effects of protein hydrolysates on cognitive performance and CBF in healthy adults and specific target populations. 4747 studies were identified, yielding 13 papers investigating cognitive performance, with four of those also evaluating CBF. Two egg-protein hydrolysates out of five studies on inhibitory control reported cognitive performance improvements. Three out of six studies from various protein sources observed enhancements in visuospatial memory. A link between CBF and cognitive performance was not observed. In conclusion, some studies have indicated that certain protein hydrolysates may benefit cognitive performance, but further research is needed to clarify contradictory findings and to identify beneficial bioactive peptides. |
| format | Article |
| id | doaj-art-af90bbc856e4473aa40118449b1cfc3a |
| institution | Kabale University |
| issn | 1756-4646 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj-art-af90bbc856e4473aa40118449b1cfc3a2025-02-09T04:59:57ZengElsevierJournal of Functional Foods1756-46462025-02-01125106683Impact of dietary protein hydrolysates on cognitive performance: A systematic review of randomized controlled trials involving adultsMicah S. Adams0Ronald P. Mensink1Peter J. Joris2Corresponding author at: Department of Nutrition and Movement Sciences, NUTRIM Research Institute of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center (MUMC)+. Universiteitssingel 50, PO Box 616, 6200, MD, Maastricht, the Netherlands.; Department of Nutrition and Movement Sciences, NUTRIM Institute of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center (MUMC)+, 6200, MD, Maastricht, the NetherlandsDepartment of Nutrition and Movement Sciences, NUTRIM Institute of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center (MUMC)+, 6200, MD, Maastricht, the NetherlandsDepartment of Nutrition and Movement Sciences, NUTRIM Institute of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center (MUMC)+, 6200, MD, Maastricht, the NetherlandsChanges in cerebral blood flow (CBF) - a marker of brain vascular function - may improve cognitive performance, and enhancing CBF through a healthy lifestyle could mitigate cognitive decline. Protein hydrolysates have shown potential to improve brain health. This systematic review analyzed randomized controlled trials on the effects of protein hydrolysates on cognitive performance and CBF in healthy adults and specific target populations. 4747 studies were identified, yielding 13 papers investigating cognitive performance, with four of those also evaluating CBF. Two egg-protein hydrolysates out of five studies on inhibitory control reported cognitive performance improvements. Three out of six studies from various protein sources observed enhancements in visuospatial memory. A link between CBF and cognitive performance was not observed. In conclusion, some studies have indicated that certain protein hydrolysates may benefit cognitive performance, but further research is needed to clarify contradictory findings and to identify beneficial bioactive peptides.http://www.sciencedirect.com/science/article/pii/S1756464625000258Protein hydrolysatesCognitive performanceBrain vascular functionCerebral blood flow |
| spellingShingle | Micah S. Adams Ronald P. Mensink Peter J. Joris Impact of dietary protein hydrolysates on cognitive performance: A systematic review of randomized controlled trials involving adults Journal of Functional Foods Protein hydrolysates Cognitive performance Brain vascular function Cerebral blood flow |
| title | Impact of dietary protein hydrolysates on cognitive performance: A systematic review of randomized controlled trials involving adults |
| title_full | Impact of dietary protein hydrolysates on cognitive performance: A systematic review of randomized controlled trials involving adults |
| title_fullStr | Impact of dietary protein hydrolysates on cognitive performance: A systematic review of randomized controlled trials involving adults |
| title_full_unstemmed | Impact of dietary protein hydrolysates on cognitive performance: A systematic review of randomized controlled trials involving adults |
| title_short | Impact of dietary protein hydrolysates on cognitive performance: A systematic review of randomized controlled trials involving adults |
| title_sort | impact of dietary protein hydrolysates on cognitive performance a systematic review of randomized controlled trials involving adults |
| topic | Protein hydrolysates Cognitive performance Brain vascular function Cerebral blood flow |
| url | http://www.sciencedirect.com/science/article/pii/S1756464625000258 |
| work_keys_str_mv | AT micahsadams impactofdietaryproteinhydrolysatesoncognitiveperformanceasystematicreviewofrandomizedcontrolledtrialsinvolvingadults AT ronaldpmensink impactofdietaryproteinhydrolysatesoncognitiveperformanceasystematicreviewofrandomizedcontrolledtrialsinvolvingadults AT peterjjoris impactofdietaryproteinhydrolysatesoncognitiveperformanceasystematicreviewofrandomizedcontrolledtrialsinvolvingadults |