Repurposing losartan potassium against rheumatoid arthritis via transdermally-delivered leciplexes: Accentuated efficacy through modulation of angiotensin II/AT1R/AT2R axis
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory ailment which preferentially impacts the synovial membranes of joints and ultimately triggers cartilage and bone erosion. Angiotensin II (Ang II) participates in the pathogenesis of RA; hence, Ang II receptor blockade, accomplished throu...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-12-01
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| Series: | International Journal of Pharmaceutics: X |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590156725000398 |
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