Assessment of the general condition and quality of life of women of post-reproductive age after asymptomatic COVID-19 and 12 months after moderate COVID-19

The aim. To assess the general condition, laboratory parameters, quality of life of women of post-reproductive age after asymptomatic COVID-19 and 12 months after moderate COVID-19.   Material and methods. We examined 47 women (45–69 years old), divided into 3 groups: those who did not have COVID-19...

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Main Authors: E. V. Vyrupaeva, N. V. Semenova, L. V. Rychkova, A. G. Petrova, M. A. Darenskaya, S. I. Kolesnikov, A. Yu. Sambyalova, L. I. Kolesnikova
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2022-12-01
Series:Acta Biomedica Scientifica
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Online Access:https://www.actabiomedica.ru/jour/article/view/3805
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author E. V. Vyrupaeva
N. V. Semenova
L. V. Rychkova
A. G. Petrova
M. A. Darenskaya
S. I. Kolesnikov
A. Yu. Sambyalova
L. I. Kolesnikova
author_facet E. V. Vyrupaeva
N. V. Semenova
L. V. Rychkova
A. G. Petrova
M. A. Darenskaya
S. I. Kolesnikov
A. Yu. Sambyalova
L. I. Kolesnikova
author_sort E. V. Vyrupaeva
collection DOAJ
description The aim. To assess the general condition, laboratory parameters, quality of life of women of post-reproductive age after asymptomatic COVID-19 and 12 months after moderate COVID-19.   Material and methods. We examined 47 women (45–69 years old), divided into 3 groups: those who did not have COVID-19, not vaccinated (group 1 – control; n = 15); women 12 months after moderate COVID-19, accompanied by pneumonia (group 2; n = 19); women with IgG in their blood who deny any symptoms of COVID-19 (group 3; n = 13).   Results and discussion. An assessment of the general condition of women in post-reproductive age was carried out. In women 12 months after COVID-19 we found a lower level of total bilirubin compared to the group with asymptomatic COVID-19 (p = 0.004). An increase in thrombin time was determined in the groups of patients with symptomatic (p = 0.014) and asymptomatic (p = 0.025) COVID-19 course compared with the control group. Patients with asymptomatic COVID-19 course had a higher level of high-density lipoprotein cholesterol compared with the control group (p = 0.016) and the group 2 (p = 0.006). Compared with the control group, the group 2 had lower scores for general health (p = 0.006), vital activity (p = 0.013), general physical well-being (p = 0.039), physical functioning (p = 0.046); and the group 3 had higher scores in role functioning due to physical condition (p = 0.049). When comparing groups 2 and 3, lower scores in the group of women who recovered from the moderate COVID-19 were found in physical functioning (p = 0.002), pain intensity (p = 0.034), role functioning due to physical condition (p = 0.049), general health (p = 0.003), vital activity (p = 0.018), general physical well-being (p = 0.001).   Conclusion. 12 months after moderate COVID-19, there is a pronounced deterioration in physical and emotional health; and in asymptomatic patients, better protective functions of an organism can be assumed.
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spelling doaj-art-af8ef1af8cbe40f284aa99e45412fdde2025-08-20T03:56:54ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962022-12-0175-1778510.29413/ABS.2022-7.5-1.92420Assessment of the general condition and quality of life of women of post-reproductive age after asymptomatic COVID-19 and 12 months after moderate COVID-19E. V. Vyrupaeva0N. V. Semenova1L. V. Rychkova2A. G. Petrova3M. A. Darenskaya4S. I. Kolesnikov5A. Yu. Sambyalova6L. I. Kolesnikova7Scientific Сentre for Family Health and Human Reproduction ProblemsScientific Сentre for Family Health and Human Reproduction ProblemsScientific Сentre for Family Health and Human Reproduction ProblemsScientific Сentre for Family Health and Human Reproduction ProblemsScientific Сentre for Family Health and Human Reproduction ProblemsScientific Сentre for Family Health and Human Reproduction ProblemsScientific Сentre for Family Health and Human Reproduction ProblemsScientific Сentre for Family Health and Human Reproduction ProblemsThe aim. To assess the general condition, laboratory parameters, quality of life of women of post-reproductive age after asymptomatic COVID-19 and 12 months after moderate COVID-19.   Material and methods. We examined 47 women (45–69 years old), divided into 3 groups: those who did not have COVID-19, not vaccinated (group 1 – control; n = 15); women 12 months after moderate COVID-19, accompanied by pneumonia (group 2; n = 19); women with IgG in their blood who deny any symptoms of COVID-19 (group 3; n = 13).   Results and discussion. An assessment of the general condition of women in post-reproductive age was carried out. In women 12 months after COVID-19 we found a lower level of total bilirubin compared to the group with asymptomatic COVID-19 (p = 0.004). An increase in thrombin time was determined in the groups of patients with symptomatic (p = 0.014) and asymptomatic (p = 0.025) COVID-19 course compared with the control group. Patients with asymptomatic COVID-19 course had a higher level of high-density lipoprotein cholesterol compared with the control group (p = 0.016) and the group 2 (p = 0.006). Compared with the control group, the group 2 had lower scores for general health (p = 0.006), vital activity (p = 0.013), general physical well-being (p = 0.039), physical functioning (p = 0.046); and the group 3 had higher scores in role functioning due to physical condition (p = 0.049). When comparing groups 2 and 3, lower scores in the group of women who recovered from the moderate COVID-19 were found in physical functioning (p = 0.002), pain intensity (p = 0.034), role functioning due to physical condition (p = 0.049), general health (p = 0.003), vital activity (p = 0.018), general physical well-being (p = 0.001).   Conclusion. 12 months after moderate COVID-19, there is a pronounced deterioration in physical and emotional health; and in asymptomatic patients, better protective functions of an organism can be assumed.https://www.actabiomedica.ru/jour/article/view/3805covid-19quality of lifewomenpost-reproductive period
spellingShingle E. V. Vyrupaeva
N. V. Semenova
L. V. Rychkova
A. G. Petrova
M. A. Darenskaya
S. I. Kolesnikov
A. Yu. Sambyalova
L. I. Kolesnikova
Assessment of the general condition and quality of life of women of post-reproductive age after asymptomatic COVID-19 and 12 months after moderate COVID-19
Acta Biomedica Scientifica
covid-19
quality of life
women
post-reproductive period
title Assessment of the general condition and quality of life of women of post-reproductive age after asymptomatic COVID-19 and 12 months after moderate COVID-19
title_full Assessment of the general condition and quality of life of women of post-reproductive age after asymptomatic COVID-19 and 12 months after moderate COVID-19
title_fullStr Assessment of the general condition and quality of life of women of post-reproductive age after asymptomatic COVID-19 and 12 months after moderate COVID-19
title_full_unstemmed Assessment of the general condition and quality of life of women of post-reproductive age after asymptomatic COVID-19 and 12 months after moderate COVID-19
title_short Assessment of the general condition and quality of life of women of post-reproductive age after asymptomatic COVID-19 and 12 months after moderate COVID-19
title_sort assessment of the general condition and quality of life of women of post reproductive age after asymptomatic covid 19 and 12 months after moderate covid 19
topic covid-19
quality of life
women
post-reproductive period
url https://www.actabiomedica.ru/jour/article/view/3805
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