Muscle Atrophy Around the Hip Joint in Patients with Femoral Neck Fracture is Associated with Postoperative Walking Ability

Introduction Patients with femoral neck fractures (FNF) have reduced walking ability owing to muscle weakness. Preoperative muscle volume and quality may have an association with prolonged rehabilitation and can be useful to predict the postoperative walking ability in patients with FNF. This study...

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Main Authors: Hyonmin Choe MD, PhD, Takahiro Yoneda MD, Masatoshi Oba MD, PhD, Koki Abe MD, PhD, Hiroyuki Ike MD, PhD, Ken Kumagai MD, PhD, Naomi Kobayashi MD, PhD, Yutaka Inaba MD, PhD
Format: Article
Language:English
Published: SAGE Publishing 2025-04-01
Series:Geriatric Orthopaedic Surgery & Rehabilitation
Online Access:https://doi.org/10.1177/21514593251336626
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author Hyonmin Choe MD, PhD
Takahiro Yoneda MD
Masatoshi Oba MD, PhD
Koki Abe MD, PhD
Hiroyuki Ike MD, PhD
Ken Kumagai MD, PhD
Naomi Kobayashi MD, PhD
Yutaka Inaba MD, PhD
author_facet Hyonmin Choe MD, PhD
Takahiro Yoneda MD
Masatoshi Oba MD, PhD
Koki Abe MD, PhD
Hiroyuki Ike MD, PhD
Ken Kumagai MD, PhD
Naomi Kobayashi MD, PhD
Yutaka Inaba MD, PhD
author_sort Hyonmin Choe MD, PhD
collection DOAJ
description Introduction Patients with femoral neck fractures (FNF) have reduced walking ability owing to muscle weakness. Preoperative muscle volume and quality may have an association with prolonged rehabilitation and can be useful to predict the postoperative walking ability in patients with FNF. This study aimed to compare the muscle volume and computed tomography (CT)-assessed density around the hip joint in patients with FNF with patients having hip osteoarthritis (HOA) and assess the association of these measurement with postoperative walking ability. Materials and Methods This retrospective observational study included 15 patients with FNF and 15 with unilateral HOA who were matched for age, sex, and osteoporosis medication. Muscle volume and CT-assessed density of the gluteus maximus, gluteus medius, gluteus minimus, iliacus, psoas major, rectus femoris, and rectus abdominis on the unaffected side were measured three-dimensionally using 3D Slicer software with preoperative CT data. The associations of muscle measurement with patient background, load to FNF (measured using the finite element method), and pre- or postoperative walking ability were assessed. Results Muscle volume of gluteus maximus, CT-assessed density of all muscles, and femoral strength were significantly lower in the FNF group than in the OA group ( P < .01, P < .01, and P = .04, respectively). Muscle volume showed a moderate-to-strong correlation with body mass index (r = 0.66-0.81) and FNF load (r = 0.51-0.70), and CT-assessed density showed a moderate correlation with serum nutritional markers (r = 0.33-0.60). Postoperative walking ability was significantly correlated with the muscle volumes of iliacus and gluteus maximus (r = 0.40 and 0.49) and CT-assessed density of all muscles (r = 0.47-0.64). Conclusion Muscle volume and CT-assessed density significantly correlated with femoral bone strength, serum total protein levels, and pre- and postoperative walking ability. These findings suggest that muscle CT analysis around the hip joint may serve as a valuable tool for assessing musculoskeletal status in patients with FNF.
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spelling doaj-art-af8db89d1ded4ed2ab2e8fef9621857f2025-08-20T02:20:06ZengSAGE PublishingGeriatric Orthopaedic Surgery & Rehabilitation2151-45932025-04-011610.1177/21514593251336626Muscle Atrophy Around the Hip Joint in Patients with Femoral Neck Fracture is Associated with Postoperative Walking AbilityHyonmin Choe MD, PhDTakahiro Yoneda MDMasatoshi Oba MD, PhDKoki Abe MD, PhDHiroyuki Ike MD, PhDKen Kumagai MD, PhDNaomi Kobayashi MD, PhDYutaka Inaba MD, PhDIntroduction Patients with femoral neck fractures (FNF) have reduced walking ability owing to muscle weakness. Preoperative muscle volume and quality may have an association with prolonged rehabilitation and can be useful to predict the postoperative walking ability in patients with FNF. This study aimed to compare the muscle volume and computed tomography (CT)-assessed density around the hip joint in patients with FNF with patients having hip osteoarthritis (HOA) and assess the association of these measurement with postoperative walking ability. Materials and Methods This retrospective observational study included 15 patients with FNF and 15 with unilateral HOA who were matched for age, sex, and osteoporosis medication. Muscle volume and CT-assessed density of the gluteus maximus, gluteus medius, gluteus minimus, iliacus, psoas major, rectus femoris, and rectus abdominis on the unaffected side were measured three-dimensionally using 3D Slicer software with preoperative CT data. The associations of muscle measurement with patient background, load to FNF (measured using the finite element method), and pre- or postoperative walking ability were assessed. Results Muscle volume of gluteus maximus, CT-assessed density of all muscles, and femoral strength were significantly lower in the FNF group than in the OA group ( P < .01, P < .01, and P = .04, respectively). Muscle volume showed a moderate-to-strong correlation with body mass index (r = 0.66-0.81) and FNF load (r = 0.51-0.70), and CT-assessed density showed a moderate correlation with serum nutritional markers (r = 0.33-0.60). Postoperative walking ability was significantly correlated with the muscle volumes of iliacus and gluteus maximus (r = 0.40 and 0.49) and CT-assessed density of all muscles (r = 0.47-0.64). Conclusion Muscle volume and CT-assessed density significantly correlated with femoral bone strength, serum total protein levels, and pre- and postoperative walking ability. These findings suggest that muscle CT analysis around the hip joint may serve as a valuable tool for assessing musculoskeletal status in patients with FNF.https://doi.org/10.1177/21514593251336626
spellingShingle Hyonmin Choe MD, PhD
Takahiro Yoneda MD
Masatoshi Oba MD, PhD
Koki Abe MD, PhD
Hiroyuki Ike MD, PhD
Ken Kumagai MD, PhD
Naomi Kobayashi MD, PhD
Yutaka Inaba MD, PhD
Muscle Atrophy Around the Hip Joint in Patients with Femoral Neck Fracture is Associated with Postoperative Walking Ability
Geriatric Orthopaedic Surgery & Rehabilitation
title Muscle Atrophy Around the Hip Joint in Patients with Femoral Neck Fracture is Associated with Postoperative Walking Ability
title_full Muscle Atrophy Around the Hip Joint in Patients with Femoral Neck Fracture is Associated with Postoperative Walking Ability
title_fullStr Muscle Atrophy Around the Hip Joint in Patients with Femoral Neck Fracture is Associated with Postoperative Walking Ability
title_full_unstemmed Muscle Atrophy Around the Hip Joint in Patients with Femoral Neck Fracture is Associated with Postoperative Walking Ability
title_short Muscle Atrophy Around the Hip Joint in Patients with Femoral Neck Fracture is Associated with Postoperative Walking Ability
title_sort muscle atrophy around the hip joint in patients with femoral neck fracture is associated with postoperative walking ability
url https://doi.org/10.1177/21514593251336626
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