Reactive astrocyte-derived exosomes enhance intracranial lymphatic drainage in mice after intracranial hemorrhage

Reactive astrocyte-derived exosomes enhance intracranial lymphatic drainage in mice after intracranial hemorrhage

Abstract Background After intracranial hemorrhage (ICH), the formation of primary hematoma foci leads to the development of secondary brain injury factors such as perihematomal edema (PHE) and accumulation of toxic metabolites, which severely affect the survival and prognosis of patients. The intrac...

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Bibliographic Details
Main Authors: Kexin Li, Yuheng Liu, Junjie Gong, Jing Li, Mingyu Zhao, Chengyou Hong, Yuchi Zhang, Mengyao He, Zhenye Zhu, Zhijuan Chen, Zengguang Wang
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Fluids and Barriers of the CNS
Subjects:
Intracranial hemorrhage
Astrocyte-derived exosomes
Glymphatic system
Online Access:https://doi.org/10.1186/s12987-025-00651-y
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