High-Grade Astroblastoma in a Young Female: An Enigma with a Rare Cautionary Tale
Astroblastoma is an uncommon neuroepithelial primary brain neoplasm with speculative histopathological origin and unpredictable clinical behavior. They can be easily misdiagnosed, as they are rarely encountered in clinical practice and share common radiological and histopathologic appearances with o...
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2023-03-01
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| Series: | Indian Journal of Neurosurgery |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1742476 |
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| author | Mukta Meel Ashok Gandhi Arpita Jindal Mukesh Kumar |
| author_facet | Mukta Meel Ashok Gandhi Arpita Jindal Mukesh Kumar |
| author_sort | Mukta Meel |
| collection | DOAJ |
| description | Astroblastoma is an uncommon neuroepithelial primary brain neoplasm with speculative histopathological origin and unpredictable clinical behavior. They can be easily misdiagnosed, as they are rarely encountered in clinical practice and share common radiological and histopathologic appearances with other glial neoplasms. Herein, we report a case of high-grade astroblastoma in a 27-year-old female with complaints of seizures and loss of consciousness, which was misdiagnosed as atypical meningioma on neuroimaging, due to its rarity and superficial cortical location appearing as extra-axial mass. Although intraoperative findings were also of an extra-axial tumor, the histology and immunophenotype was of an astroblastoma; thus, highlighting the role of histopathology and immunohistochemistry. |
| format | Article |
| id | doaj-art-af825299ea8a4272a0b1eeddcf69aeb7 |
| institution | OA Journals |
| issn | 2277-954X 2277-9167 |
| language | English |
| publishDate | 2023-03-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Neurosurgery |
| spelling | doaj-art-af825299ea8a4272a0b1eeddcf69aeb72025-08-20T02:23:16ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Neurosurgery2277-954X2277-91672023-03-01120108608910.1055/s-0042-1742476High-Grade Astroblastoma in a Young Female: An Enigma with a Rare Cautionary TaleMukta Meel0Ashok Gandhi1Arpita Jindal2Mukesh Kumar3Department of Pathology, SMS Medical College, Jaipur, Rajasthan, IndiaDepartment of Neurosurgery, SMS Medical College, Jaipur, Rajasthan, IndiaDepartment of Pathology, SMS Medical College, Jaipur, Rajasthan, IndiaDepartment of Neurosurgery, SMS Medical College, Jaipur, Rajasthan, IndiaAstroblastoma is an uncommon neuroepithelial primary brain neoplasm with speculative histopathological origin and unpredictable clinical behavior. They can be easily misdiagnosed, as they are rarely encountered in clinical practice and share common radiological and histopathologic appearances with other glial neoplasms. Herein, we report a case of high-grade astroblastoma in a 27-year-old female with complaints of seizures and loss of consciousness, which was misdiagnosed as atypical meningioma on neuroimaging, due to its rarity and superficial cortical location appearing as extra-axial mass. Although intraoperative findings were also of an extra-axial tumor, the histology and immunophenotype was of an astroblastoma; thus, highlighting the role of histopathology and immunohistochemistry.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1742476astroblastomahistologyneuroepithelial brain tumor |
| spellingShingle | Mukta Meel Ashok Gandhi Arpita Jindal Mukesh Kumar High-Grade Astroblastoma in a Young Female: An Enigma with a Rare Cautionary Tale Indian Journal of Neurosurgery astroblastoma histology neuroepithelial brain tumor |
| title | High-Grade Astroblastoma in a Young Female: An Enigma with a Rare Cautionary Tale |
| title_full | High-Grade Astroblastoma in a Young Female: An Enigma with a Rare Cautionary Tale |
| title_fullStr | High-Grade Astroblastoma in a Young Female: An Enigma with a Rare Cautionary Tale |
| title_full_unstemmed | High-Grade Astroblastoma in a Young Female: An Enigma with a Rare Cautionary Tale |
| title_short | High-Grade Astroblastoma in a Young Female: An Enigma with a Rare Cautionary Tale |
| title_sort | high grade astroblastoma in a young female an enigma with a rare cautionary tale |
| topic | astroblastoma histology neuroepithelial brain tumor |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1742476 |
| work_keys_str_mv | AT muktameel highgradeastroblastomainayoungfemaleanenigmawithararecautionarytale AT ashokgandhi highgradeastroblastomainayoungfemaleanenigmawithararecautionarytale AT arpitajindal highgradeastroblastomainayoungfemaleanenigmawithararecautionarytale AT mukeshkumar highgradeastroblastomainayoungfemaleanenigmawithararecautionarytale |