Structure-activity relationship of PET-degrading cutinase regulated by weak Ca2+ binding and temperature
Enzyme function is often regulated by weak metal-ion binding, which results from conformational changes while maintaining conformational fluctuations. We analyzed the structure and function of cutinase-like enzyme, Cut190, using biophysical methods such as X-ray crystallography and molecular dynamic...
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| Main Authors: | Fumiya Kondo, Narutoshi Kamiya, Gert-Jan Bekker, Satoshi Nagao, Nobutaka Numoto, Hiroshi Sekiguchi, Nobutoshi Ito, Masayuki Oda |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The Biophysical Society of Japan
2025-05-01
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| Series: | Biophysics and Physicobiology |
| Subjects: | |
| Online Access: | https://doi.org/10.2142/biophysico.bppb-v22.0009 |
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