Dexmedetomidine Induced Polyuria in the Intensive Care Unit

Dexmedetomidine is an α2-adrenergic used as an adjunct therapy for sedation in the intensive care unit. While it is known to cause polyuria exclusively in perioperative conditions, not many cases are known in the intensive care unit, thus making the diagnosis challenging. We present the case of a 61...

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Main Authors: Mohammed M. Uddin, Joseph Sebastian, Muhammad Usama, Fazal I. Raziq, Ghulam Saydain, Noreen F. Rossi
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Critical Care
Online Access:http://dx.doi.org/10.1155/2021/8850116
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author Mohammed M. Uddin
Joseph Sebastian
Muhammad Usama
Fazal I. Raziq
Ghulam Saydain
Noreen F. Rossi
author_facet Mohammed M. Uddin
Joseph Sebastian
Muhammad Usama
Fazal I. Raziq
Ghulam Saydain
Noreen F. Rossi
author_sort Mohammed M. Uddin
collection DOAJ
description Dexmedetomidine is an α2-adrenergic used as an adjunct therapy for sedation in the intensive care unit. While it is known to cause polyuria exclusively in perioperative conditions, not many cases are known in the intensive care unit, thus making the diagnosis challenging. We present the case of a 61-year-old male who had developed polyuria secondary to central diabetes insipidus after receiving dexmedetomidine intravenous infusion in the medical ICU. Increased awareness of this uncommon side effect of dexmedetomidine will help clinicians recognize and address it early.
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issn 2090-6420
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publishDate 2021-01-01
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series Case Reports in Critical Care
spelling doaj-art-af6b8fbe4f09498fb570ae358bf6cf742025-08-20T02:23:16ZengWileyCase Reports in Critical Care2090-64202090-64392021-01-01202110.1155/2021/88501168850116Dexmedetomidine Induced Polyuria in the Intensive Care UnitMohammed M. Uddin0Joseph Sebastian1Muhammad Usama2Fazal I. Raziq3Ghulam Saydain4Noreen F. Rossi5Internal Medicine, Wayne State University/Detroit Medical Center, 4201 St Antoine, Detroit, MI 48201, USAInternal Medicine, Wayne State University/Detroit Medical Center, 4201 St Antoine, Detroit, MI 48201, USAInternal Medicine, Wayne State University/Detroit Medical Center, 4201 St Antoine, Detroit, MI 48201, USAInternal Medicine, Michigan State University/Sparrow Hospital, 1215 E Michigan Ave, Lansing, MI 48912, USAPulmonary Criticasl Care & Sleep Division, Wayne State University/Detroit Medical Center, 4201 St Antoine, Detroit, MI 48201, USADivision of Nephrology, Wayne State University/Detroit Medical Center, 4201 St Antoine, Detroit, MI 48201, USADexmedetomidine is an α2-adrenergic used as an adjunct therapy for sedation in the intensive care unit. While it is known to cause polyuria exclusively in perioperative conditions, not many cases are known in the intensive care unit, thus making the diagnosis challenging. We present the case of a 61-year-old male who had developed polyuria secondary to central diabetes insipidus after receiving dexmedetomidine intravenous infusion in the medical ICU. Increased awareness of this uncommon side effect of dexmedetomidine will help clinicians recognize and address it early.http://dx.doi.org/10.1155/2021/8850116
spellingShingle Mohammed M. Uddin
Joseph Sebastian
Muhammad Usama
Fazal I. Raziq
Ghulam Saydain
Noreen F. Rossi
Dexmedetomidine Induced Polyuria in the Intensive Care Unit
Case Reports in Critical Care
title Dexmedetomidine Induced Polyuria in the Intensive Care Unit
title_full Dexmedetomidine Induced Polyuria in the Intensive Care Unit
title_fullStr Dexmedetomidine Induced Polyuria in the Intensive Care Unit
title_full_unstemmed Dexmedetomidine Induced Polyuria in the Intensive Care Unit
title_short Dexmedetomidine Induced Polyuria in the Intensive Care Unit
title_sort dexmedetomidine induced polyuria in the intensive care unit
url http://dx.doi.org/10.1155/2021/8850116
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