A ten-year histopathological study of generalised lymphadenopathy in India
Background: Lymphadenopathy is a rather common clinical finding in a primary healthcare setting, and may be due to inflammatory lesions and tumours. Correlation between clinical findings and laboratory data is essential in arriving at a diagnosis. This study was undertaken to study the histopatholog...
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2011-07-01
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| Series: | South African Family Practice |
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| author | G.C. Kamat |
| author_facet | G.C. Kamat |
| author_sort | G.C. Kamat |
| collection | DOAJ |
| description | Background: Lymphadenopathy is a rather common clinical finding in a primary healthcare setting, and may be due to inflammatory lesions and tumours. Correlation between clinical findings and laboratory data is essential in arriving at a diagnosis. This study was undertaken to study the histopathology of generalised lymphadenopathy in India, as well as the demographics of the study population.
Method: This study was conducted for a period of 10 years (August 1997-July 2007), of which eight years were retrospective, from August 1997-July 2005, and two years were prospective, from August 2005-July 2007. The source of data for this study was patients seeking medical attention, who, on clinical examination, were found to have generalised lymphadenopathy. A representative node was excised for histopathology. Tissues were routinely processed, stained with haematoxylin and eosin, and examined by means of light microscopy.
Results: Of the 244 lymph node biopsies analysed in this study, 75 cases (30.73%) were reactive lymphadenitis, 142 cases (58.19%) showed granulomatous lymphadenitis, one case (0.40%) was Hodgkin’s lymphoma, eight cases (3.27%) were non-Hodgkin’s lymphoma, and 18 cases (7.37%) were metastatic malignancy.
Conclusion: In this study, the most common cause of generalised lymphadenopathy was granulomatous lymphadenitis, followed by reactive lymphadenitis. Among the neoplastic lesions, metastatic malignancy accounted for most cases. |
| format | Article |
| id | doaj-art-af6b80a1a2024e08a768e8e48fa17266 |
| institution | DOAJ |
| issn | 2078-6190 2078-6204 |
| language | English |
| publishDate | 2011-07-01 |
| publisher | AOSIS |
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| series | South African Family Practice |
| spelling | doaj-art-af6b80a1a2024e08a768e8e48fa172662025-08-20T03:07:09ZengAOSISSouth African Family Practice2078-61902078-62042011-07-0153310.1080/20786204.2011.108740974567A ten-year histopathological study of generalised lymphadenopathy in IndiaG.C. Kamat0SDM College of Medical Sciences and HospitalBackground: Lymphadenopathy is a rather common clinical finding in a primary healthcare setting, and may be due to inflammatory lesions and tumours. Correlation between clinical findings and laboratory data is essential in arriving at a diagnosis. This study was undertaken to study the histopathology of generalised lymphadenopathy in India, as well as the demographics of the study population. Method: This study was conducted for a period of 10 years (August 1997-July 2007), of which eight years were retrospective, from August 1997-July 2005, and two years were prospective, from August 2005-July 2007. The source of data for this study was patients seeking medical attention, who, on clinical examination, were found to have generalised lymphadenopathy. A representative node was excised for histopathology. Tissues were routinely processed, stained with haematoxylin and eosin, and examined by means of light microscopy. Results: Of the 244 lymph node biopsies analysed in this study, 75 cases (30.73%) were reactive lymphadenitis, 142 cases (58.19%) showed granulomatous lymphadenitis, one case (0.40%) was Hodgkin’s lymphoma, eight cases (3.27%) were non-Hodgkin’s lymphoma, and 18 cases (7.37%) were metastatic malignancy. Conclusion: In this study, the most common cause of generalised lymphadenopathy was granulomatous lymphadenitis, followed by reactive lymphadenitis. Among the neoplastic lesions, metastatic malignancy accounted for most cases.https://safpj.co.za/index.php/safpj/article/view/1636lymphadenopathylymph nodelymphadenitislymphomalymph node biopsy |
| spellingShingle | G.C. Kamat A ten-year histopathological study of generalised lymphadenopathy in India South African Family Practice lymphadenopathy lymph node lymphadenitis lymphoma lymph node biopsy |
| title | A ten-year histopathological study of generalised lymphadenopathy in India |
| title_full | A ten-year histopathological study of generalised lymphadenopathy in India |
| title_fullStr | A ten-year histopathological study of generalised lymphadenopathy in India |
| title_full_unstemmed | A ten-year histopathological study of generalised lymphadenopathy in India |
| title_short | A ten-year histopathological study of generalised lymphadenopathy in India |
| title_sort | ten year histopathological study of generalised lymphadenopathy in india |
| topic | lymphadenopathy lymph node lymphadenitis lymphoma lymph node biopsy |
| url | https://safpj.co.za/index.php/safpj/article/view/1636 |
| work_keys_str_mv | AT gckamat atenyearhistopathologicalstudyofgeneralisedlymphadenopathyinindia AT gckamat tenyearhistopathologicalstudyofgeneralisedlymphadenopathyinindia |