MAML2-Rearranged Primary Central Mucoepidermoid Carcinoma of the Mandible as an Incidental Finding: A Case Report and Review of the Literature of Molecularly Confirmed Cases
This report presents an extremely rare case of MAML2-rearranged primary central mucoepidermoid carcinoma (MEC) of the mandible that was discovered as an incidental finding. Our review of the literature identified 36 cases of MAML2-rearranged intraosseous lesions of the jaw (30 central MECs, 5 odonto...
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | Case Reports in Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2023/7764292 |
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| _version_ | 1832546756919820288 |
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| author | Sarah E. Aguirre Donald Tyler Adepitan A. Owosho |
| author_facet | Sarah E. Aguirre Donald Tyler Adepitan A. Owosho |
| author_sort | Sarah E. Aguirre |
| collection | DOAJ |
| description | This report presents an extremely rare case of MAML2-rearranged primary central mucoepidermoid carcinoma (MEC) of the mandible that was discovered as an incidental finding. Our review of the literature identified 36 cases of MAML2-rearranged intraosseous lesions of the jaw (30 central MECs, 5 odontogenic cysts with mucous prosoplasia, and 1 glandular odontogenic cyst). Given the therapeutic indications for a diagnosis of MEC (a malignant neoplasm), MAML2 rearrangement should be confirmed in suspected cases of central MEC. |
| format | Article |
| id | doaj-art-af5a4bb2f9ea4f829c6b9f914f8daba3 |
| institution | Kabale University |
| issn | 2090-6455 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dentistry |
| spelling | doaj-art-af5a4bb2f9ea4f829c6b9f914f8daba32025-02-03T06:47:17ZengWileyCase Reports in Dentistry2090-64552023-01-01202310.1155/2023/7764292MAML2-Rearranged Primary Central Mucoepidermoid Carcinoma of the Mandible as an Incidental Finding: A Case Report and Review of the Literature of Molecularly Confirmed CasesSarah E. Aguirre0Donald Tyler1Adepitan A. Owosho2Department of Diagnostic SciencesJoint Base San Antonio-Lackland Air Force BaseDepartment of Diagnostic SciencesThis report presents an extremely rare case of MAML2-rearranged primary central mucoepidermoid carcinoma (MEC) of the mandible that was discovered as an incidental finding. Our review of the literature identified 36 cases of MAML2-rearranged intraosseous lesions of the jaw (30 central MECs, 5 odontogenic cysts with mucous prosoplasia, and 1 glandular odontogenic cyst). Given the therapeutic indications for a diagnosis of MEC (a malignant neoplasm), MAML2 rearrangement should be confirmed in suspected cases of central MEC.http://dx.doi.org/10.1155/2023/7764292 |
| spellingShingle | Sarah E. Aguirre Donald Tyler Adepitan A. Owosho MAML2-Rearranged Primary Central Mucoepidermoid Carcinoma of the Mandible as an Incidental Finding: A Case Report and Review of the Literature of Molecularly Confirmed Cases Case Reports in Dentistry |
| title | MAML2-Rearranged Primary Central Mucoepidermoid Carcinoma of the Mandible as an Incidental Finding: A Case Report and Review of the Literature of Molecularly Confirmed Cases |
| title_full | MAML2-Rearranged Primary Central Mucoepidermoid Carcinoma of the Mandible as an Incidental Finding: A Case Report and Review of the Literature of Molecularly Confirmed Cases |
| title_fullStr | MAML2-Rearranged Primary Central Mucoepidermoid Carcinoma of the Mandible as an Incidental Finding: A Case Report and Review of the Literature of Molecularly Confirmed Cases |
| title_full_unstemmed | MAML2-Rearranged Primary Central Mucoepidermoid Carcinoma of the Mandible as an Incidental Finding: A Case Report and Review of the Literature of Molecularly Confirmed Cases |
| title_short | MAML2-Rearranged Primary Central Mucoepidermoid Carcinoma of the Mandible as an Incidental Finding: A Case Report and Review of the Literature of Molecularly Confirmed Cases |
| title_sort | maml2 rearranged primary central mucoepidermoid carcinoma of the mandible as an incidental finding a case report and review of the literature of molecularly confirmed cases |
| url | http://dx.doi.org/10.1155/2023/7764292 |
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