Severe late onset capillary leak syndrome post allo-HSCT successfully treated by bevacizumab: a case report
This article describes a case of successful management of late-onset CLS occurring after allo-HSCT, employing bevacizumab as the therapeutic agent. Capillary leak syndrome (CLS) represents a critical complication arising from allogeneic hematopoietic stem cell transplantation (allo-HSCT). The progno...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2024.1483064/full |
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| author | Song Xue Jiaqi Chen Yuzhu Shi Lina Zhang Man Chen Huipeng Sun Xingyu Cao Fang Wu |
| author_facet | Song Xue Jiaqi Chen Yuzhu Shi Lina Zhang Man Chen Huipeng Sun Xingyu Cao Fang Wu |
| author_sort | Song Xue |
| collection | DOAJ |
| description | This article describes a case of successful management of late-onset CLS occurring after allo-HSCT, employing bevacizumab as the therapeutic agent. Capillary leak syndrome (CLS) represents a critical complication arising from allogeneic hematopoietic stem cell transplantation (allo-HSCT). The prognosis for CLS remains considerably constrained. A targeted therapeutic approach targeting vascular endothelial growth factor (VEGF) offers a novel strategy for the management of CLS. |
| format | Article |
| id | doaj-art-af57ee065e9246b78fc796d6819ee6bb |
| institution | Kabale University |
| issn | 2296-858X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-af57ee065e9246b78fc796d6819ee6bb2025-01-07T05:24:07ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-01-011110.3389/fmed.2024.14830641483064Severe late onset capillary leak syndrome post allo-HSCT successfully treated by bevacizumab: a case reportSong Xue0Jiaqi Chen1Yuzhu Shi2Lina Zhang3Man Chen4Huipeng Sun5Xingyu Cao6Fang Wu7Department of Bone Marrow Transplant, Beijing Lu Daopei Hospital, Beijing, ChinaDepartment of Laboratory Medicine, Hebei Yanda Lu Daopei Hospital, Langfang, ChinaDepartment of Radiology, Beijing Lu Daopei Hospital, Beijing, ChinaDivision of Pathology and Laboratory Medicine, Beijing Lu Daopei Hospital, Beijing, ChinaDivision of Pathology and Laboratory Medicine, Beijing Lu Daopei Hospital, Beijing, ChinaDivision of Pathology and Laboratory Medicine, Beijing Lu Daopei Hospital, Beijing, ChinaDepartment of Bone Marrow Transplant, Hebei Yanda Lu Daopei Hospital, Langfang, ChinaPharmacy Department, Beijing Lu Daopei Hospital, Beijing, ChinaThis article describes a case of successful management of late-onset CLS occurring after allo-HSCT, employing bevacizumab as the therapeutic agent. Capillary leak syndrome (CLS) represents a critical complication arising from allogeneic hematopoietic stem cell transplantation (allo-HSCT). The prognosis for CLS remains considerably constrained. A targeted therapeutic approach targeting vascular endothelial growth factor (VEGF) offers a novel strategy for the management of CLS.https://www.frontiersin.org/articles/10.3389/fmed.2024.1483064/fullcapillary leak syndrome (CLS)allo-HSCTbevacizumab (avastin)case reportvascular endothelial growth factor (VEGF) |
| spellingShingle | Song Xue Jiaqi Chen Yuzhu Shi Lina Zhang Man Chen Huipeng Sun Xingyu Cao Fang Wu Severe late onset capillary leak syndrome post allo-HSCT successfully treated by bevacizumab: a case report Frontiers in Medicine capillary leak syndrome (CLS) allo-HSCT bevacizumab (avastin) case report vascular endothelial growth factor (VEGF) |
| title | Severe late onset capillary leak syndrome post allo-HSCT successfully treated by bevacizumab: a case report |
| title_full | Severe late onset capillary leak syndrome post allo-HSCT successfully treated by bevacizumab: a case report |
| title_fullStr | Severe late onset capillary leak syndrome post allo-HSCT successfully treated by bevacizumab: a case report |
| title_full_unstemmed | Severe late onset capillary leak syndrome post allo-HSCT successfully treated by bevacizumab: a case report |
| title_short | Severe late onset capillary leak syndrome post allo-HSCT successfully treated by bevacizumab: a case report |
| title_sort | severe late onset capillary leak syndrome post allo hsct successfully treated by bevacizumab a case report |
| topic | capillary leak syndrome (CLS) allo-HSCT bevacizumab (avastin) case report vascular endothelial growth factor (VEGF) |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2024.1483064/full |
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