2D versus 3D tumor-on-chip models to study the impact of tumor organization on metabolic patterns in vitro
Abstract Despite the limitations of in vitro models to investigate cancer cell metabolism, their study can provide new insights essential for understanding tumorigenesis and effectively aiding in the development of novel therapies. The innovative tumor-on-chip models offer a more physiologically rel...
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| Main Authors: | Paula Guerrero-López, Ana Martín-Pardillos, Javier Bonet-Aleta, Andrea Mosseri, Jose L. Hueso, Jesus Santamaria, Jose Manuel Garcia-Aznar |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-06-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-03504-8 |
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