Clinical characteristics, imaging features, and fate of punctate outer retinal toxoplasmosis lesions in immunocompetent cases of ocular toxoplasmosis
PURPOSE: The purpose of this study was to study clinical characteristics, imaging features, and fate of punctate outer retinal toxoplasmosis (PORT). MATERIALS AND METHODS: A retrospective, observational, descriptive analysis of PORT lesions presenting as satellite lesions of typical full-thickness n...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-04-01
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| Series: | Taiwan Journal of Ophthalmology |
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| Online Access: | https://journals.lww.com/10.4103/tjo.TJO-D-25-00011 |
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| author | Anup Kelgaonkar Vishal Jadhav Anamika Patel Soumyava Basu Avinash Pathengay |
| author_facet | Anup Kelgaonkar Vishal Jadhav Anamika Patel Soumyava Basu Avinash Pathengay |
| author_sort | Anup Kelgaonkar |
| collection | DOAJ |
| description | PURPOSE:
The purpose of this study was to study clinical characteristics, imaging features, and fate of punctate outer retinal toxoplasmosis (PORT).
MATERIALS AND METHODS:
A retrospective, observational, descriptive analysis of PORT lesions presenting as satellite lesions of typical full-thickness necrotizing Toxoplasma retinochoroiditis (TRC) or isolated lesions in immunocompetent cases.
RESULTS:
We analyzed 34 eyes of 34 cases (22 males and 12 females). PORT lesions appeared as deep, dull, yellowish-gray outer retinal lesions, either as satellite lesions to a TRC (n = 30) or isolated macular punctate lesions (n = 4). The mean lesion size was 562 μm (50–1000). The recurrence rate was high (23.52%), manifesting as either typical TRC (n = 4) or new satellite PORT lesions (n = 4). Active lesions had hyperreflective outer retinal foci on optical coherence tomography (OCT), hyperautofluorescent in the active phase, and stippled upon resolution. Healed lesions exhibited outer nuclear layer thinning and outer retinal atrophy on OCT and were hypoautofluorescent.
CONCLUSION:
PORT lesions were observed as multiple punctate lesions, either adjacent to TRC in active or healed phases or as isolated macular punctate toxoplasmosis. Autofluorescence, angiography, and OCT assist in differentiating active from healed lesions. The fate of PORT lesions was healing with granularity, fading, or complete resolution. Some cases recurred with new satellite PORT lesions, whereas others progressed to typical retinochoroiditis or CNVM. |
| format | Article |
| id | doaj-art-af55d5230f594556bc73820c09656d8a |
| institution | Kabale University |
| issn | 2211-5056 2211-5072 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Taiwan Journal of Ophthalmology |
| spelling | doaj-art-af55d5230f594556bc73820c09656d8a2025-08-20T03:31:48ZengWolters Kluwer Medknow PublicationsTaiwan Journal of Ophthalmology2211-50562211-50722025-04-0115227027610.4103/tjo.TJO-D-25-00011Clinical characteristics, imaging features, and fate of punctate outer retinal toxoplasmosis lesions in immunocompetent cases of ocular toxoplasmosisAnup KelgaonkarVishal JadhavAnamika PatelSoumyava BasuAvinash PathengayPURPOSE: The purpose of this study was to study clinical characteristics, imaging features, and fate of punctate outer retinal toxoplasmosis (PORT). MATERIALS AND METHODS: A retrospective, observational, descriptive analysis of PORT lesions presenting as satellite lesions of typical full-thickness necrotizing Toxoplasma retinochoroiditis (TRC) or isolated lesions in immunocompetent cases. RESULTS: We analyzed 34 eyes of 34 cases (22 males and 12 females). PORT lesions appeared as deep, dull, yellowish-gray outer retinal lesions, either as satellite lesions to a TRC (n = 30) or isolated macular punctate lesions (n = 4). The mean lesion size was 562 μm (50–1000). The recurrence rate was high (23.52%), manifesting as either typical TRC (n = 4) or new satellite PORT lesions (n = 4). Active lesions had hyperreflective outer retinal foci on optical coherence tomography (OCT), hyperautofluorescent in the active phase, and stippled upon resolution. Healed lesions exhibited outer nuclear layer thinning and outer retinal atrophy on OCT and were hypoautofluorescent. CONCLUSION: PORT lesions were observed as multiple punctate lesions, either adjacent to TRC in active or healed phases or as isolated macular punctate toxoplasmosis. Autofluorescence, angiography, and OCT assist in differentiating active from healed lesions. The fate of PORT lesions was healing with granularity, fading, or complete resolution. Some cases recurred with new satellite PORT lesions, whereas others progressed to typical retinochoroiditis or CNVM.https://journals.lww.com/10.4103/tjo.TJO-D-25-00011autofluorescencefundus fluorescence angiographymacular punctate toxoplasmosisocular toxoplasmosisoptical coherence tomographypunctate inner retinal toxoplasmosispunctate outer retinal toxoplasmosistoxoplasma gondiitoxoplasma retinitistoxoplasma retinochoroiditis |
| spellingShingle | Anup Kelgaonkar Vishal Jadhav Anamika Patel Soumyava Basu Avinash Pathengay Clinical characteristics, imaging features, and fate of punctate outer retinal toxoplasmosis lesions in immunocompetent cases of ocular toxoplasmosis Taiwan Journal of Ophthalmology autofluorescence fundus fluorescence angiography macular punctate toxoplasmosis ocular toxoplasmosis optical coherence tomography punctate inner retinal toxoplasmosis punctate outer retinal toxoplasmosis toxoplasma gondii toxoplasma retinitis toxoplasma retinochoroiditis |
| title | Clinical characteristics, imaging features, and fate of punctate outer retinal toxoplasmosis lesions in immunocompetent cases of ocular toxoplasmosis |
| title_full | Clinical characteristics, imaging features, and fate of punctate outer retinal toxoplasmosis lesions in immunocompetent cases of ocular toxoplasmosis |
| title_fullStr | Clinical characteristics, imaging features, and fate of punctate outer retinal toxoplasmosis lesions in immunocompetent cases of ocular toxoplasmosis |
| title_full_unstemmed | Clinical characteristics, imaging features, and fate of punctate outer retinal toxoplasmosis lesions in immunocompetent cases of ocular toxoplasmosis |
| title_short | Clinical characteristics, imaging features, and fate of punctate outer retinal toxoplasmosis lesions in immunocompetent cases of ocular toxoplasmosis |
| title_sort | clinical characteristics imaging features and fate of punctate outer retinal toxoplasmosis lesions in immunocompetent cases of ocular toxoplasmosis |
| topic | autofluorescence fundus fluorescence angiography macular punctate toxoplasmosis ocular toxoplasmosis optical coherence tomography punctate inner retinal toxoplasmosis punctate outer retinal toxoplasmosis toxoplasma gondii toxoplasma retinitis toxoplasma retinochoroiditis |
| url | https://journals.lww.com/10.4103/tjo.TJO-D-25-00011 |
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