Malignant Intracerebral Nerve Sheath Tumors: A Case Report with Review of the Literature
The occurrence of benign nerve sheath tumors within the neuroaxis is uncommon. Even rarer is the finding within brain parenchyma, termed malignant intracerebral nerve sheath tumors (MINST). We present a case of MINST which occurred in the frontal lobe of an 18-year-old male that recurred almost 4 ye...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2013/384076 |
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| author | Faris Shweikeh Doniel Drazin Sergei I. Bannykh |
| author_facet | Faris Shweikeh Doniel Drazin Sergei I. Bannykh |
| author_sort | Faris Shweikeh |
| collection | DOAJ |
| description | The occurrence of benign nerve sheath tumors within the neuroaxis is uncommon. Even rarer is the finding within brain parenchyma, termed malignant intracerebral nerve sheath tumors (MINST). We present a case of MINST which occurred in the frontal lobe of an 18-year-old male that recurred almost 4 years later. Imaging demonstrated a 4.0 cm lesion with an associated mass effect. He underwent a right fronto-parietal craniotomy for gross total resection. Pathology was inconclusive with a Glioblastoma Multiforme (GBM) as the most likely diagnosis, though gliosarcoma and MINST were also highly considered. Postoperatively, he was treated with chemotherapy and radiation and followed for almost 4 years, when an MRI indicated a recurrence. Resection of the recurrence was highly suggestive of MINST. Surgery was followed by radiation and chemotherapy, but, less than 7 months later, he was readmitted for a surgical-site infection, and, after multiple surgeries, and his family terminated care. Recognizing this unusual tumor in the differential diagnosis of a heterogeneously enhancing intracerebral mass can help surgeons diagnose and treat it. This report also exhaustively reviews the literature and presents diagnostic and treatment strategies. |
| format | Article |
| id | doaj-art-af4cd3ab3554432994f52b4dc1c83593 |
| institution | OA Journals |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-af4cd3ab3554432994f52b4dc1c835932025-08-20T02:19:07ZengWileyCase Reports in Surgery2090-69002090-69192013-01-01201310.1155/2013/384076384076Malignant Intracerebral Nerve Sheath Tumors: A Case Report with Review of the LiteratureFaris Shweikeh0Doniel Drazin1Sergei I. Bannykh2Department of Neurosurgery, Cedars-Sinai Medical Center, Maxine Dunitz Neurosurgical Institute, Los Angeles, CA 90048, USADepartment of Neurosurgery, Cedars-Sinai Medical Center, Maxine Dunitz Neurosurgical Institute, Los Angeles, CA 90048, USADepartment of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USAThe occurrence of benign nerve sheath tumors within the neuroaxis is uncommon. Even rarer is the finding within brain parenchyma, termed malignant intracerebral nerve sheath tumors (MINST). We present a case of MINST which occurred in the frontal lobe of an 18-year-old male that recurred almost 4 years later. Imaging demonstrated a 4.0 cm lesion with an associated mass effect. He underwent a right fronto-parietal craniotomy for gross total resection. Pathology was inconclusive with a Glioblastoma Multiforme (GBM) as the most likely diagnosis, though gliosarcoma and MINST were also highly considered. Postoperatively, he was treated with chemotherapy and radiation and followed for almost 4 years, when an MRI indicated a recurrence. Resection of the recurrence was highly suggestive of MINST. Surgery was followed by radiation and chemotherapy, but, less than 7 months later, he was readmitted for a surgical-site infection, and, after multiple surgeries, and his family terminated care. Recognizing this unusual tumor in the differential diagnosis of a heterogeneously enhancing intracerebral mass can help surgeons diagnose and treat it. This report also exhaustively reviews the literature and presents diagnostic and treatment strategies.http://dx.doi.org/10.1155/2013/384076 |
| spellingShingle | Faris Shweikeh Doniel Drazin Sergei I. Bannykh Malignant Intracerebral Nerve Sheath Tumors: A Case Report with Review of the Literature Case Reports in Surgery |
| title | Malignant Intracerebral Nerve Sheath Tumors: A Case Report with Review of the Literature |
| title_full | Malignant Intracerebral Nerve Sheath Tumors: A Case Report with Review of the Literature |
| title_fullStr | Malignant Intracerebral Nerve Sheath Tumors: A Case Report with Review of the Literature |
| title_full_unstemmed | Malignant Intracerebral Nerve Sheath Tumors: A Case Report with Review of the Literature |
| title_short | Malignant Intracerebral Nerve Sheath Tumors: A Case Report with Review of the Literature |
| title_sort | malignant intracerebral nerve sheath tumors a case report with review of the literature |
| url | http://dx.doi.org/10.1155/2013/384076 |
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