MGA directly recruits SETDB1/ATF7IP for histone H3K9me3 mark on meiosis-related genes in mouse embryonic stem cells

MGA directly recruits SETDB1/ATF7IP for histone H3K9me3 mark on meiosis-related genes in mouse embryonic stem cells

Summary: Polycomb repressive complex 1.6 (PRC1.6), one of the PRC1 subtypes, plays crucial roles in preventing the ectopic expression of meiosis-related genes in mouse embryonic stem cells (ESCs). In addition to the histone modifications H2AK119ub1 and H3K27me3 that are deposited by PRC1 and PRC2, r...

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Bibliographic Details
Main Authors: Kousuke Uranishi, Masataka Hirasaki, Masazumi Nishimoto, Robert J. Klose, Akihiko Okuda, Ayumu Suzuki
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:iScience
Subjects:
Biochemistry
Cell biology
Stem cells research
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225013203
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