Screening and hit evaluation of a microbial metabolite library against the pathogenic Plasmodium falciparum and Toxoplasma gondii parasites

Frontline drug treatments for malaria are at risk of failing due to emerging resistance, meanwhile drugs used to treat toxoplasmosis have suboptimal efficacy and safety. As demonstrated by the success of clinically used antiparasitic drugs, the diverse structural complexity and biological activity o...

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Bibliographic Details
Main Authors: Maria R. Gancheva, Emma Y. Mao, Ornella Romeo, Daniel Vuong, Ryan O'Handley, Stephen W. Page, Ernest Lacey, Danny W. Wilson
Format: Article
Language:English
Published: Elsevier 2025-12-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211320725000296
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