Prophylactic and biocontrol effect of the microencapsulated lactic acid bacteria extracted from honey bee gut against some diseases of the honey bee, Apis mellifera L.

Abstract Background American foulbrood (AFB), Nosemosis and Varroasis are diseases that affect honey bee health and their products. The present study evaluated microencapsulated lactic acid bacteria (LAB) as a novel technique for the biocontrol of these diseases. Double coated microencapsulation was...

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Main Authors: Fatma Mahmoud, Rasha M. A. Farag, Shireen A. M. Ma’moun, Ahmed S. Abou Zeid, Akila M. El Shafei, Eman E. Essa
Format: Article
Language:English
Published: SpringerOpen 2025-04-01
Series:Egyptian Journal of Biological Pest Control
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Online Access:https://doi.org/10.1186/s41938-025-00850-7
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author Fatma Mahmoud
Rasha M. A. Farag
Shireen A. M. Ma’moun
Ahmed S. Abou Zeid
Akila M. El Shafei
Eman E. Essa
author_facet Fatma Mahmoud
Rasha M. A. Farag
Shireen A. M. Ma’moun
Ahmed S. Abou Zeid
Akila M. El Shafei
Eman E. Essa
author_sort Fatma Mahmoud
collection DOAJ
description Abstract Background American foulbrood (AFB), Nosemosis and Varroasis are diseases that affect honey bee health and their products. The present study evaluated microencapsulated lactic acid bacteria (LAB) as a novel technique for the biocontrol of these diseases. Double coated microencapsulation was performed for the preservation of five different locally isolated, honey bee endogenous LABs (Lactobacillus plantarum MK780211, L. plantarum MK780215, L. kunkeei MK780216, L. kunkeei MK780218, and Lactobacillus sp. MK780212). Results In vivo, twenty-seven colonies of honey bees of equal strength and queens of the same age were divided into seven treatments and compared with a control. There were different observations on the honey bee colonies according to their treatments. Honey bee colonies that were supplied with LAB microcapsules alternatively; with Fumidil®B and with formic acid had the highest increase in growth curves. The treatments that had a moderate increase in growth curves were the honey bee colonies treated with LAB microcapsules only and LAB microcapsules alternatively with Sulphamethoxazole, with Thymol, with both “Sulphamethoxazole and Thymol” and with both “Fumidil®B and Thymol”. Finally, honey bee colonies that were supplied with Sulphamethoxazole, Thymol, Fumidil®B and formic acid without LAB microcapsules (−ve control) had a slight increase in growth curves that was lower than normal. The honey bee colonies without any treatments (+ ve control) collapsed since the first three months of the experiment. Conclusion Honey bee colonies could be supplemented with microencapsulated LABs, alternatively with low concentrations of traditional honeybee treatments such as Fumidil®B and formic acid to achieve maximum protection from diseases.
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spelling doaj-art-af40ec150214484aa2fbd5c81d85813b2025-08-20T02:28:08ZengSpringerOpenEgyptian Journal of Biological Pest Control2536-93422025-04-0135111510.1186/s41938-025-00850-7Prophylactic and biocontrol effect of the microencapsulated lactic acid bacteria extracted from honey bee gut against some diseases of the honey bee, Apis mellifera L.Fatma Mahmoud0Rasha M. A. Farag1Shireen A. M. Ma’moun2Ahmed S. Abou Zeid3Akila M. El Shafei4Eman E. Essa5Entomology Department, Faculty of Science, Ain Shams UniversityHoneybee Research Department, Agriculture Research Centre, Plant Protection Research Institute, DokkiEntomology Department, Faculty of Science, Ain Shams UniversityEntomology Department, Faculty of Science, Ain Shams UniversityEntomology Department, Faculty of Science, Ain Shams UniversityEntomology Department, Faculty of Science, Ain Shams UniversityAbstract Background American foulbrood (AFB), Nosemosis and Varroasis are diseases that affect honey bee health and their products. The present study evaluated microencapsulated lactic acid bacteria (LAB) as a novel technique for the biocontrol of these diseases. Double coated microencapsulation was performed for the preservation of five different locally isolated, honey bee endogenous LABs (Lactobacillus plantarum MK780211, L. plantarum MK780215, L. kunkeei MK780216, L. kunkeei MK780218, and Lactobacillus sp. MK780212). Results In vivo, twenty-seven colonies of honey bees of equal strength and queens of the same age were divided into seven treatments and compared with a control. There were different observations on the honey bee colonies according to their treatments. Honey bee colonies that were supplied with LAB microcapsules alternatively; with Fumidil®B and with formic acid had the highest increase in growth curves. The treatments that had a moderate increase in growth curves were the honey bee colonies treated with LAB microcapsules only and LAB microcapsules alternatively with Sulphamethoxazole, with Thymol, with both “Sulphamethoxazole and Thymol” and with both “Fumidil®B and Thymol”. Finally, honey bee colonies that were supplied with Sulphamethoxazole, Thymol, Fumidil®B and formic acid without LAB microcapsules (−ve control) had a slight increase in growth curves that was lower than normal. The honey bee colonies without any treatments (+ ve control) collapsed since the first three months of the experiment. Conclusion Honey bee colonies could be supplemented with microencapsulated LABs, alternatively with low concentrations of traditional honeybee treatments such as Fumidil®B and formic acid to achieve maximum protection from diseases.https://doi.org/10.1186/s41938-025-00850-7American foulbroodNosemosisVarroasisMicroencapsulationLactic acid bacteria
spellingShingle Fatma Mahmoud
Rasha M. A. Farag
Shireen A. M. Ma’moun
Ahmed S. Abou Zeid
Akila M. El Shafei
Eman E. Essa
Prophylactic and biocontrol effect of the microencapsulated lactic acid bacteria extracted from honey bee gut against some diseases of the honey bee, Apis mellifera L.
Egyptian Journal of Biological Pest Control
American foulbrood
Nosemosis
Varroasis
Microencapsulation
Lactic acid bacteria
title Prophylactic and biocontrol effect of the microencapsulated lactic acid bacteria extracted from honey bee gut against some diseases of the honey bee, Apis mellifera L.
title_full Prophylactic and biocontrol effect of the microencapsulated lactic acid bacteria extracted from honey bee gut against some diseases of the honey bee, Apis mellifera L.
title_fullStr Prophylactic and biocontrol effect of the microencapsulated lactic acid bacteria extracted from honey bee gut against some diseases of the honey bee, Apis mellifera L.
title_full_unstemmed Prophylactic and biocontrol effect of the microencapsulated lactic acid bacteria extracted from honey bee gut against some diseases of the honey bee, Apis mellifera L.
title_short Prophylactic and biocontrol effect of the microencapsulated lactic acid bacteria extracted from honey bee gut against some diseases of the honey bee, Apis mellifera L.
title_sort prophylactic and biocontrol effect of the microencapsulated lactic acid bacteria extracted from honey bee gut against some diseases of the honey bee apis mellifera l
topic American foulbrood
Nosemosis
Varroasis
Microencapsulation
Lactic acid bacteria
url https://doi.org/10.1186/s41938-025-00850-7
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