The Role of Single Dose Heparin in Prevention of Thrombus Formation in a New Experimental Thrombosis Model
Vascular thrombosis continues to remain a major problem in microvascular surgery. Various antithrombotic agents have been used in experimental models in order to study their influence on the incidence of thrombosis. A new microvascular thrombosis model which utilizes a crushing artery forceps on the...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Thieme Medical and Scientific Publishers Pvt. Ltd.
1995-02-01
|
| Series: | Indian Journal of Plastic Surgery |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1774668 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849397183492653056 |
|---|---|
| author | V Nanda R K Khazanchi K Rakshit P Chopra |
| author_facet | V Nanda R K Khazanchi K Rakshit P Chopra |
| author_sort | V Nanda |
| collection | DOAJ |
| description | Vascular thrombosis continues to remain a major problem in microvascular surgery. Various antithrombotic agents have been used in experimental models in order to study their influence on the incidence of thrombosis. A new microvascular thrombosis model which utilizes a crushing artery forceps on the rat femoral vessels was used to evaluate the effect of a single does of heparin administered subcutaneously just prior to release of the crushing clamp. Patency across the traumatized segments was determined after 24 hours, by the “milking” test and by dividing the vessels downstream to the site of trauma. |
| format | Article |
| id | doaj-art-af2ed873045146c4b64fe8c6cb7c200c |
| institution | Kabale University |
| issn | 0970-0358 1998-376X |
| language | English |
| publishDate | 1995-02-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Plastic Surgery |
| spelling | doaj-art-af2ed873045146c4b64fe8c6cb7c200c2025-08-20T03:39:06ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Plastic Surgery0970-03581998-376X1995-02-01280100100410.1055/s-0043-1774668The Role of Single Dose Heparin in Prevention of Thrombus Formation in a New Experimental Thrombosis ModelV Nanda0R K Khazanchi1K Rakshit2P Chopra3Division of Reconstructive Surgery, Department of Surgical Disciplines, All India Institute of Medical Sciences, N DelhiDivision of Reconstructive Surgery, Department of Surgical Disciplines, All India Institute of Medical Sciences, N DelhiDivision of Reconstructive Surgery, Department of Surgical Disciplines, All India Institute of Medical Sciences, N DelhiDepartment of Pathology, All India Institute of Medical Sciences, N DelhiVascular thrombosis continues to remain a major problem in microvascular surgery. Various antithrombotic agents have been used in experimental models in order to study their influence on the incidence of thrombosis. A new microvascular thrombosis model which utilizes a crushing artery forceps on the rat femoral vessels was used to evaluate the effect of a single does of heparin administered subcutaneously just prior to release of the crushing clamp. Patency across the traumatized segments was determined after 24 hours, by the “milking” test and by dividing the vessels downstream to the site of trauma.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1774668 |
| spellingShingle | V Nanda R K Khazanchi K Rakshit P Chopra The Role of Single Dose Heparin in Prevention of Thrombus Formation in a New Experimental Thrombosis Model Indian Journal of Plastic Surgery |
| title | The Role of Single Dose Heparin in Prevention of Thrombus Formation in a New Experimental Thrombosis Model |
| title_full | The Role of Single Dose Heparin in Prevention of Thrombus Formation in a New Experimental Thrombosis Model |
| title_fullStr | The Role of Single Dose Heparin in Prevention of Thrombus Formation in a New Experimental Thrombosis Model |
| title_full_unstemmed | The Role of Single Dose Heparin in Prevention of Thrombus Formation in a New Experimental Thrombosis Model |
| title_short | The Role of Single Dose Heparin in Prevention of Thrombus Formation in a New Experimental Thrombosis Model |
| title_sort | role of single dose heparin in prevention of thrombus formation in a new experimental thrombosis model |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1774668 |
| work_keys_str_mv | AT vnanda theroleofsingledoseheparininpreventionofthrombusformationinanewexperimentalthrombosismodel AT rkkhazanchi theroleofsingledoseheparininpreventionofthrombusformationinanewexperimentalthrombosismodel AT krakshit theroleofsingledoseheparininpreventionofthrombusformationinanewexperimentalthrombosismodel AT pchopra theroleofsingledoseheparininpreventionofthrombusformationinanewexperimentalthrombosismodel AT vnanda roleofsingledoseheparininpreventionofthrombusformationinanewexperimentalthrombosismodel AT rkkhazanchi roleofsingledoseheparininpreventionofthrombusformationinanewexperimentalthrombosismodel AT krakshit roleofsingledoseheparininpreventionofthrombusformationinanewexperimentalthrombosismodel AT pchopra roleofsingledoseheparininpreventionofthrombusformationinanewexperimentalthrombosismodel |