An Unusual Presentation of Adenoid Cystic Carcinoma

Adenoid cystic carcinoma (ACC) is a relatively rare tumor of epithelial cell origin, most commonly arising from major salivary glands. It is uncommonly found outside the major or minor salivary glands and is especially rare when located in the nasal cavity. Diagnosis and treatment of ACC pose numero...

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Main Authors: Kurren S. Gill, Mark A. Frattali
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Otolaryngology
Online Access:http://dx.doi.org/10.1155/2015/826436
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author Kurren S. Gill
Mark A. Frattali
author_facet Kurren S. Gill
Mark A. Frattali
author_sort Kurren S. Gill
collection DOAJ
description Adenoid cystic carcinoma (ACC) is a relatively rare tumor of epithelial cell origin, most commonly arising from major salivary glands. It is uncommonly found outside the major or minor salivary glands and is especially rare when located in the nasal cavity. Diagnosis and treatment of ACC pose numerous challenges, partly due to its biological behavior of slow growth, high tendency of local recurrence, and perineural invasion. We present the case of a 67-year-old male with complaints of facial pain and swelling, with a CT scan showing a soft tissue mass extending from the right nasal cavity with osseous destruction. Biopsy revealed ACC with perineural invasion. ACC of the nasal cavity continues to pose diagnostic and therapeutic challenges to physicians. Because this rare pathology presents in a vague manner, early diagnosis requires a high index of suspicion for this disease and close follow-up care. Since ACC of the nasal cavity is seldom reported in the literature, it is our hope that reporting these rare instances as case reports will heighten physician awareness of this rare disease, allowing for early diagnosis and treatment.
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spelling doaj-art-af28d352002346589a6c276e6f79b5312025-02-03T01:07:46ZengWileyCase Reports in Otolaryngology2090-67652090-67732015-01-01201510.1155/2015/826436826436An Unusual Presentation of Adenoid Cystic CarcinomaKurren S. Gill0Mark A. Frattali1The Commonwealth Medical College, 525 Pine Street, Scranton, PA 18509, USAThe Commonwealth Medical College, 525 Pine Street, Scranton, PA 18509, USAAdenoid cystic carcinoma (ACC) is a relatively rare tumor of epithelial cell origin, most commonly arising from major salivary glands. It is uncommonly found outside the major or minor salivary glands and is especially rare when located in the nasal cavity. Diagnosis and treatment of ACC pose numerous challenges, partly due to its biological behavior of slow growth, high tendency of local recurrence, and perineural invasion. We present the case of a 67-year-old male with complaints of facial pain and swelling, with a CT scan showing a soft tissue mass extending from the right nasal cavity with osseous destruction. Biopsy revealed ACC with perineural invasion. ACC of the nasal cavity continues to pose diagnostic and therapeutic challenges to physicians. Because this rare pathology presents in a vague manner, early diagnosis requires a high index of suspicion for this disease and close follow-up care. Since ACC of the nasal cavity is seldom reported in the literature, it is our hope that reporting these rare instances as case reports will heighten physician awareness of this rare disease, allowing for early diagnosis and treatment.http://dx.doi.org/10.1155/2015/826436
spellingShingle Kurren S. Gill
Mark A. Frattali
An Unusual Presentation of Adenoid Cystic Carcinoma
Case Reports in Otolaryngology
title An Unusual Presentation of Adenoid Cystic Carcinoma
title_full An Unusual Presentation of Adenoid Cystic Carcinoma
title_fullStr An Unusual Presentation of Adenoid Cystic Carcinoma
title_full_unstemmed An Unusual Presentation of Adenoid Cystic Carcinoma
title_short An Unusual Presentation of Adenoid Cystic Carcinoma
title_sort unusual presentation of adenoid cystic carcinoma
url http://dx.doi.org/10.1155/2015/826436
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