Both CYP2C19 and PON1 Q192R Genotypes Influence Platelet Response to Clopidogrel by Thrombelastography in Patients with Acute Coronary Syndrome

Both CYP2C19 and PON1 Q192R Genotypes Influence Platelet Response to Clopidogrel by Thrombelastography in Patients with Acute Coronary Syndrome

Objective. The objective of this study is to explore the relationships of the effects of CYP2C19 and PON1 Q192R polymorphism on the activity of clopidogrel and the risk of high platelet responsiveness (HPR) by thrombelastography in patients with acute coronary syndrome (ACS). Methods. 459 ACS patien...

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Bibliographic Details
Main Authors: Wenxing Peng, Xiujin Shi, Xiaoyu Xu, Yang Lin
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Cardiovascular Therapeutics
Online Access:http://dx.doi.org/10.1155/2019/3470145
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