Cauda equina enhancing lesion in a HIV-positive patient. Case report and literature revision.

We describe the case a spinal cord localization of neurological toxoplasmosis in a HIV-positive patient with Burkitt lymphoma, previously treated with chemotherapy and immunotherapy. This complication occurred while patient was in complete remission of lymphoma, with CD4+ T cell count of 270 /ml, u...

Full description

Saved in:
Bibliographic Details
Main Authors: Pasquale De Bonis, Antonella Cingolani, Angelo Pompucci, Tommaso Tartaglione, Luigi Maria Larocca, Luciana Teofili
Format: Article
Language:English
Published: PAGEPress Publications 2011-10-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
Subjects:
Online Access:http://www.mjhid.org/index.php/mjhid/article/view/324
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850215529686499328
author Pasquale De Bonis
Antonella Cingolani
Angelo Pompucci
Tommaso Tartaglione
Luigi Maria Larocca
Luciana Teofili
author_facet Pasquale De Bonis
Antonella Cingolani
Angelo Pompucci
Tommaso Tartaglione
Luigi Maria Larocca
Luciana Teofili
author_sort Pasquale De Bonis
collection DOAJ
description We describe the case a spinal cord localization of neurological toxoplasmosis in a HIV-positive patient with Burkitt lymphoma, previously treated with chemotherapy and immunotherapy. This complication occurred while patient was in complete remission of lymphoma, with CD4+ T cell count of 270 /ml, undetectable HIV viremia, and despite the trimethoprim/ sulfamethoxazole prophylaxis. Indeed, we hypothesize that in our patient neurologic toxoplasmosis has been fostered more by previous immuno-chemotherapy than by HIV- related immunodeficiency. On the whole, this case suggests that parameters usually employed to predict the risk for opportunistic infections in HIV-positive people might not apply to patients with HIV-related lymphomas.
format Article
id doaj-art-af1e499b704a4fee9258a7e07de2caa8
institution OA Journals
issn 2035-3006
language English
publishDate 2011-10-01
publisher PAGEPress Publications
record_format Article
series Mediterranean Journal of Hematology and Infectious Diseases
spelling doaj-art-af1e499b704a4fee9258a7e07de2caa82025-08-20T02:08:35ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062011-10-0131e2011042e201104210.4084/mjhid.2011.042216Cauda equina enhancing lesion in a HIV-positive patient. Case report and literature revision.Pasquale De BonisAntonella CingolaniAngelo PompucciTommaso TartaglioneLuigi Maria LaroccaLuciana TeofiliWe describe the case a spinal cord localization of neurological toxoplasmosis in a HIV-positive patient with Burkitt lymphoma, previously treated with chemotherapy and immunotherapy. This complication occurred while patient was in complete remission of lymphoma, with CD4+ T cell count of 270 /ml, undetectable HIV viremia, and despite the trimethoprim/ sulfamethoxazole prophylaxis. Indeed, we hypothesize that in our patient neurologic toxoplasmosis has been fostered more by previous immuno-chemotherapy than by HIV- related immunodeficiency. On the whole, this case suggests that parameters usually employed to predict the risk for opportunistic infections in HIV-positive people might not apply to patients with HIV-related lymphomas.http://www.mjhid.org/index.php/mjhid/article/view/324HIV, Lymphoma, Parassitosis
spellingShingle Pasquale De Bonis
Antonella Cingolani
Angelo Pompucci
Tommaso Tartaglione
Luigi Maria Larocca
Luciana Teofili
Cauda equina enhancing lesion in a HIV-positive patient. Case report and literature revision.
Mediterranean Journal of Hematology and Infectious Diseases
HIV, Lymphoma, Parassitosis
title Cauda equina enhancing lesion in a HIV-positive patient. Case report and literature revision.
title_full Cauda equina enhancing lesion in a HIV-positive patient. Case report and literature revision.
title_fullStr Cauda equina enhancing lesion in a HIV-positive patient. Case report and literature revision.
title_full_unstemmed Cauda equina enhancing lesion in a HIV-positive patient. Case report and literature revision.
title_short Cauda equina enhancing lesion in a HIV-positive patient. Case report and literature revision.
title_sort cauda equina enhancing lesion in a hiv positive patient case report and literature revision
topic HIV, Lymphoma, Parassitosis
url http://www.mjhid.org/index.php/mjhid/article/view/324
work_keys_str_mv AT pasqualedebonis caudaequinaenhancinglesioninahivpositivepatientcasereportandliteraturerevision
AT antonellacingolani caudaequinaenhancinglesioninahivpositivepatientcasereportandliteraturerevision
AT angelopompucci caudaequinaenhancinglesioninahivpositivepatientcasereportandliteraturerevision
AT tommasotartaglione caudaequinaenhancinglesioninahivpositivepatientcasereportandliteraturerevision
AT luigimarialarocca caudaequinaenhancinglesioninahivpositivepatientcasereportandliteraturerevision
AT lucianateofili caudaequinaenhancinglesioninahivpositivepatientcasereportandliteraturerevision