Evaluation of vascular invasion in hepatic alveolar echinococcosis using computed tomography: An observational study
Objective: Alveolar echinococcosis (AE) is a severe, chronic parasitic disease predominantly affecting the liver. Surgical intervention is the only definitive treatment, but vascular invasion significantly increases surgical risks. This study aimed to identify factors associated with vascular invasi...
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| Format: | Article |
| Language: | English |
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Center for Scientific Research and Development of Education.
2025-03-01
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| Series: | Heart Vessels and Transplantation |
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| Online Access: | https://hvt-journal.com/articles/art553 |
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| author | Ilyar A. Baudinov Aliya I. Kadyrova Kanat Omorov Bakhadyr K. Bebezov Kubat Ibraimov Aleksei Oginskiy Roshan Kumar Shah Shabdan N. Isamadyrov |
| author_facet | Ilyar A. Baudinov Aliya I. Kadyrova Kanat Omorov Bakhadyr K. Bebezov Kubat Ibraimov Aleksei Oginskiy Roshan Kumar Shah Shabdan N. Isamadyrov |
| author_sort | Ilyar A. Baudinov |
| collection | DOAJ |
| description | Objective: Alveolar echinococcosis (AE) is a severe, chronic parasitic disease predominantly affecting the liver. Surgical intervention is the only definitive treatment, but vascular invasion significantly increases surgical risks. This study aimed to identify factors associated with vascular invasion in hepatic AE to improve diagnosis and surgical planning.
Methods: A retrospective analysis of 70 patients with newly diagnosed hepatic AE was conducted using contrast enhanced computed tomography (CT). Factors including sex, age, number and size of foci, lesion volume, and the morphologic type of lesions (based on the Alveolar Echinococcosis Ulm Classification, AEUC) were evaluated for their association with blood vessel invasion. Statistical analyses included cross-tabulations and symmetric measures, with significance assessed at p < 0.05.
Results: Among the variables analyzed, the number of foci and the size of the largest focus were identified as significant predictors of vascular invasion, with Cramer's V values of 0.404 (p=0.022) and 0.630 (p=0.066), respectively. Other factors, including sex, age, lesion volume, and AEUC morphological type, showed weaker or statistically insignificant associations with vascular involvement.
Conclusion: The invasion of parasitic nodules into large blood vessels in patients with first diagnosed hepatic AE does not depend directly on sex, age, type of focus according to AEUC. It can be stated that with a high probability invasion of pathologic focus into the vascular wall is associated with an increase in the volume of liver lesion. The most significant predictors of invasion into large vessels are the number of foci and the size of the largest foci. |
| format | Article |
| id | doaj-art-af094ec36d504f449f19637458e0f969 |
| institution | Kabale University |
| issn | 1694-7886 1694-7894 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Center for Scientific Research and Development of Education. |
| record_format | Article |
| series | Heart Vessels and Transplantation |
| spelling | doaj-art-af094ec36d504f449f19637458e0f9692025-08-20T03:44:33ZengCenter for Scientific Research and Development of Education.Heart Vessels and Transplantation1694-78861694-78942025-03-019110.24969/hvt.2024.553Evaluation of vascular invasion in hepatic alveolar echinococcosis using computed tomography: An observational studyIlyar A. Baudinov0Aliya I. Kadyrova1Kanat Omorov2Bakhadyr K. Bebezov3Kubat Ibraimov4Aleksei Oginskiy5 Roshan Kumar Shah6Shabdan N. Isamadyrov7Department of Radiology, I.K. Akhunbaev Kyrgyz State Medical Academy, Bishkek, KyrgyzstanDepartment of Radiology, I.K. Akhunbaev Kyrgyz State Medical Academy, Bishkek, KyrgyzstanDepartment of Faculty Surgery named after Academician K.R. Ryskulova, I.K. Akhunbaev Kyrgyz State Medical Academy, Bishkek, KyrgyzstanDepartment of Innovative Surgical Technologies, I.K. Akhunbaev Kyrgyz State Medical Academy, Bishkek, KyrgyzstanDepartment of Radiology, I.K. Akhunbaev Kyrgyz State Medical Academy, Bishkek, KyrgyzstanDepartment of Radiology, I.K. Akhunbaev Kyrgyz State Medical Academy, Bishkek, KyrgyzstanDepartment of Radiology, I.K. Akhunbaev Kyrgyz State Medical Academy, Bishkek, KyrgyzstanDepartment of Radiology, I.K. Akhunbaev Kyrgyz State Medical Academy, Bishkek, KyrgyzstanObjective: Alveolar echinococcosis (AE) is a severe, chronic parasitic disease predominantly affecting the liver. Surgical intervention is the only definitive treatment, but vascular invasion significantly increases surgical risks. This study aimed to identify factors associated with vascular invasion in hepatic AE to improve diagnosis and surgical planning. Methods: A retrospective analysis of 70 patients with newly diagnosed hepatic AE was conducted using contrast enhanced computed tomography (CT). Factors including sex, age, number and size of foci, lesion volume, and the morphologic type of lesions (based on the Alveolar Echinococcosis Ulm Classification, AEUC) were evaluated for their association with blood vessel invasion. Statistical analyses included cross-tabulations and symmetric measures, with significance assessed at p < 0.05. Results: Among the variables analyzed, the number of foci and the size of the largest focus were identified as significant predictors of vascular invasion, with Cramer's V values of 0.404 (p=0.022) and 0.630 (p=0.066), respectively. Other factors, including sex, age, lesion volume, and AEUC morphological type, showed weaker or statistically insignificant associations with vascular involvement. Conclusion: The invasion of parasitic nodules into large blood vessels in patients with first diagnosed hepatic AE does not depend directly on sex, age, type of focus according to AEUC. It can be stated that with a high probability invasion of pathologic focus into the vascular wall is associated with an increase in the volume of liver lesion. The most significant predictors of invasion into large vessels are the number of foci and the size of the largest foci.https://hvt-journal.com/articles/art553alveococcosisalveolar echinococcosisechinococcus multiloculariscomputed tomographyliverliver vessels |
| spellingShingle | Ilyar A. Baudinov Aliya I. Kadyrova Kanat Omorov Bakhadyr K. Bebezov Kubat Ibraimov Aleksei Oginskiy Roshan Kumar Shah Shabdan N. Isamadyrov Evaluation of vascular invasion in hepatic alveolar echinococcosis using computed tomography: An observational study Heart Vessels and Transplantation alveococcosis alveolar echinococcosis echinococcus multilocularis computed tomography liver liver vessels |
| title | Evaluation of vascular invasion in hepatic alveolar echinococcosis using computed tomography: An observational study |
| title_full | Evaluation of vascular invasion in hepatic alveolar echinococcosis using computed tomography: An observational study |
| title_fullStr | Evaluation of vascular invasion in hepatic alveolar echinococcosis using computed tomography: An observational study |
| title_full_unstemmed | Evaluation of vascular invasion in hepatic alveolar echinococcosis using computed tomography: An observational study |
| title_short | Evaluation of vascular invasion in hepatic alveolar echinococcosis using computed tomography: An observational study |
| title_sort | evaluation of vascular invasion in hepatic alveolar echinococcosis using computed tomography an observational study |
| topic | alveococcosis alveolar echinococcosis echinococcus multilocularis computed tomography liver liver vessels |
| url | https://hvt-journal.com/articles/art553 |
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