Statistically verified methods for determining predictors of development of arterial hypertension depending on endothelial nitric oxide synthase T786C gene promoter polymorphism using lipid profile indicators
Objective. Polymorphism investigation of T786C gene promoter of endothelial nitric oxide synthase (eNOS/NOS3) in the arterial hypertension is a promising field for determining the relationship between heredity, hypertension, and dyslipidemia, which still remains controversial. The purpose of the stu...
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| Format: | Article |
| Language: | English |
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Sciendo
2024-01-01
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| Series: | Endocrine Regulations |
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| Online Access: | https://doi.org/10.2478/enr-2024-0015 |
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| author | Pidruchna Svitlana Shmanko Volodimir Hnizdyukh Roman Sverstiuk Andrii Lykhatskyy Petro Kuzmak Iryna Yaroshenko Tetyana Bandas Iryna Vasylyshyn Nadya Ostrivka Oksana Mudra Alla Palytsia Lylya Letnyak Nataliya Tokarskyy Oleksandr |
| author_facet | Pidruchna Svitlana Shmanko Volodimir Hnizdyukh Roman Sverstiuk Andrii Lykhatskyy Petro Kuzmak Iryna Yaroshenko Tetyana Bandas Iryna Vasylyshyn Nadya Ostrivka Oksana Mudra Alla Palytsia Lylya Letnyak Nataliya Tokarskyy Oleksandr |
| author_sort | Pidruchna Svitlana |
| collection | DOAJ |
| description | Objective. Polymorphism investigation of T786C gene promoter of endothelial nitric oxide synthase (eNOS/NOS3) in the arterial hypertension is a promising field for determining the relationship between heredity, hypertension, and dyslipidemia, which still remains controversial. The purpose of the study was to investigate the lipid profile, which depends on the NOS3 T786C gene promotor region polymorphism in patients with arterial hypertension. |
| format | Article |
| id | doaj-art-af021c68a88e47a483402567b7dedd3f |
| institution | OA Journals |
| issn | 1336-0329 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Endocrine Regulations |
| spelling | doaj-art-af021c68a88e47a483402567b7dedd3f2025-08-20T01:53:33ZengSciendoEndocrine Regulations1336-03292024-01-0158113814310.2478/enr-2024-0015Statistically verified methods for determining predictors of development of arterial hypertension depending on endothelial nitric oxide synthase T786C gene promoter polymorphism using lipid profile indicatorsPidruchna Svitlana0Shmanko Volodimir1Hnizdyukh Roman2Sverstiuk Andrii3Lykhatskyy Petro4Kuzmak Iryna5Yaroshenko Tetyana6Bandas Iryna7Vasylyshyn Nadya8Ostrivka Oksana9Mudra Alla10Palytsia Lylya11Letnyak Nataliya12Tokarskyy Oleksandr13Department of Medical BiochemistryDepartment of Farmacology and Clinical FarmacologyDepartment of Farmacology and Clinical FarmacologyDepartment of Medical Informatics, I. Horbachevsky Ternopil National Medical University of the Ministry of Health of UkraineTernopil, UkraineDepartment of Medical BiochemistryDepartment of Medical BiochemistryDepartment of Medical BiochemistryDepartment of Medical BiochemistryDepartment of Medical BiochemistryDepartment of Medical BiochemistryDepartment of Medical BiochemistryDepartment of Medical BiochemistryDepartment of Medical BiochemistryDepartment of Medical BiochemistryObjective. Polymorphism investigation of T786C gene promoter of endothelial nitric oxide synthase (eNOS/NOS3) in the arterial hypertension is a promising field for determining the relationship between heredity, hypertension, and dyslipidemia, which still remains controversial. The purpose of the study was to investigate the lipid profile, which depends on the NOS3 T786C gene promotor region polymorphism in patients with arterial hypertension.https://doi.org/10.2478/enr-2024-0015arterial hypertensionendothelial nitric oxide synthase t786c promotor region polymorphismlipidogram |
| spellingShingle | Pidruchna Svitlana Shmanko Volodimir Hnizdyukh Roman Sverstiuk Andrii Lykhatskyy Petro Kuzmak Iryna Yaroshenko Tetyana Bandas Iryna Vasylyshyn Nadya Ostrivka Oksana Mudra Alla Palytsia Lylya Letnyak Nataliya Tokarskyy Oleksandr Statistically verified methods for determining predictors of development of arterial hypertension depending on endothelial nitric oxide synthase T786C gene promoter polymorphism using lipid profile indicators Endocrine Regulations arterial hypertension endothelial nitric oxide synthase t786c promotor region polymorphism lipidogram |
| title | Statistically verified methods for determining predictors of development of arterial hypertension depending on endothelial nitric oxide synthase T786C gene promoter polymorphism using lipid profile indicators |
| title_full | Statistically verified methods for determining predictors of development of arterial hypertension depending on endothelial nitric oxide synthase T786C gene promoter polymorphism using lipid profile indicators |
| title_fullStr | Statistically verified methods for determining predictors of development of arterial hypertension depending on endothelial nitric oxide synthase T786C gene promoter polymorphism using lipid profile indicators |
| title_full_unstemmed | Statistically verified methods for determining predictors of development of arterial hypertension depending on endothelial nitric oxide synthase T786C gene promoter polymorphism using lipid profile indicators |
| title_short | Statistically verified methods for determining predictors of development of arterial hypertension depending on endothelial nitric oxide synthase T786C gene promoter polymorphism using lipid profile indicators |
| title_sort | statistically verified methods for determining predictors of development of arterial hypertension depending on endothelial nitric oxide synthase t786c gene promoter polymorphism using lipid profile indicators |
| topic | arterial hypertension endothelial nitric oxide synthase t786c promotor region polymorphism lipidogram |
| url | https://doi.org/10.2478/enr-2024-0015 |
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