Alterations in GSH/GSSG and CyS/CySS redox status in small cell lung cancer patients undergoing chemotherapy
Abstract Background In small cell lung cancer (SCLC), oxidative stress disrupts redox balance and contributes to tumor progression and treatment resistance through DNA damage, inflammation, and tumorigenesis. Thiol compounds such as glutathione (GSH) and cysteine (CyS) together with their oxidized f...
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| Main Authors: | Azra Guzonjić, Milkica Crevar, Ivana Simić, Natalija Samardzić, Vesna Ćeriman Krstić, Jelena Kotur Stevuljević, Dragana Jovanović |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-07-01
|
| Series: | Discover Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s12672-025-03251-2 |
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