A Computational Methodology Based on Maximum Overlap Discrete Wavelet Transform and Autoencoders for Early Prediction of Sudden Cardiac Death

Cardiovascular diseases are among the major global health problems. For example, sudden cardiac death (SCD) accounts for approximately 4 million deaths worldwide. In particular, an SCD event can subtly change the electrocardiogram (ECG) signal before onset, which is generally undetectable by the pat...

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Main Authors: Manuel A. Centeno-Bautista, Andrea V. Perez-Sanchez, Juan P. Amezquita-Sanchez, David Camarena-Martinez, Martin Valtierra-Rodriguez
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Computation
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Online Access:https://www.mdpi.com/2079-3197/13/6/130
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author Manuel A. Centeno-Bautista
Andrea V. Perez-Sanchez
Juan P. Amezquita-Sanchez
David Camarena-Martinez
Martin Valtierra-Rodriguez
author_facet Manuel A. Centeno-Bautista
Andrea V. Perez-Sanchez
Juan P. Amezquita-Sanchez
David Camarena-Martinez
Martin Valtierra-Rodriguez
author_sort Manuel A. Centeno-Bautista
collection DOAJ
description Cardiovascular diseases are among the major global health problems. For example, sudden cardiac death (SCD) accounts for approximately 4 million deaths worldwide. In particular, an SCD event can subtly change the electrocardiogram (ECG) signal before onset, which is generally undetectable by the patient. Hence, timely detection of these changes in ECG signals could help develop a tool to anticipate an SCD event and respond appropriately in patient care. In this sense, this work proposes a novel computational methodology that combines the maximal overlap discrete wavelet packet transform (MODWPT) with stacked autoencoders (SAEs) to discover suitable features in ECG signals and associate them with SCD prediction. The proposed method efficiently predicts an SCD event with an accuracy of 98.94% up to 30 min before the onset, making it a reliable tool for early detection while providing sufficient time for medical intervention and increasing the chances of preventing fatal outcomes, demonstrating the potential of integrating signal processing and deep learning techniques within computational biology to address life-critical health problems.
format Article
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institution Kabale University
issn 2079-3197
language English
publishDate 2025-06-01
publisher MDPI AG
record_format Article
series Computation
spelling doaj-art-aef5feb22c004a02b11cbc18ed581a6b2025-08-20T03:26:11ZengMDPI AGComputation2079-31972025-06-0113613010.3390/computation13060130A Computational Methodology Based on Maximum Overlap Discrete Wavelet Transform and Autoencoders for Early Prediction of Sudden Cardiac DeathManuel A. Centeno-Bautista0Andrea V. Perez-Sanchez1Juan P. Amezquita-Sanchez2David Camarena-Martinez3Martin Valtierra-Rodriguez4ENAP-RG, CA Sistemas Dinámicos y Control, Facultad de Ingeniería, Departamento de Electromecánica, Universidad Autónoma de Querétaro, Campus San Juan del Río, San Juan del Río 76807, MexicoENAP-RG, CA Sistemas Dinámicos y Control, Facultad de Ingeniería, Departamento de Electromecánica, Universidad Autónoma de Querétaro, Campus San Juan del Río, San Juan del Río 76807, MexicoENAP-RG, CA Sistemas Dinámicos y Control, Facultad de Ingeniería, Departamento de Electromecánica, Universidad Autónoma de Querétaro, Campus San Juan del Río, San Juan del Río 76807, MexicoENAP-RG, División de Ingeniería, Universidad de Guanajuato (UG), Campus Irapuato-Salamanca, Carretera Salamanca-Valle de Santiago km 3.5 + 1.8 km, Comunidad de Palo Blanco, Salamanca 36885, MexicoENAP-RG, CA Sistemas Dinámicos y Control, Facultad de Ingeniería, Departamento de Electromecánica, Universidad Autónoma de Querétaro, Campus San Juan del Río, San Juan del Río 76807, MexicoCardiovascular diseases are among the major global health problems. For example, sudden cardiac death (SCD) accounts for approximately 4 million deaths worldwide. In particular, an SCD event can subtly change the electrocardiogram (ECG) signal before onset, which is generally undetectable by the patient. Hence, timely detection of these changes in ECG signals could help develop a tool to anticipate an SCD event and respond appropriately in patient care. In this sense, this work proposes a novel computational methodology that combines the maximal overlap discrete wavelet packet transform (MODWPT) with stacked autoencoders (SAEs) to discover suitable features in ECG signals and associate them with SCD prediction. The proposed method efficiently predicts an SCD event with an accuracy of 98.94% up to 30 min before the onset, making it a reliable tool for early detection while providing sufficient time for medical intervention and increasing the chances of preventing fatal outcomes, demonstrating the potential of integrating signal processing and deep learning techniques within computational biology to address life-critical health problems.https://www.mdpi.com/2079-3197/13/6/130sudden cardiac deathelectrocardiogram signalmaximum overlap discrete wavelet packet transformstacked autoencodersdeep learning
spellingShingle Manuel A. Centeno-Bautista
Andrea V. Perez-Sanchez
Juan P. Amezquita-Sanchez
David Camarena-Martinez
Martin Valtierra-Rodriguez
A Computational Methodology Based on Maximum Overlap Discrete Wavelet Transform and Autoencoders for Early Prediction of Sudden Cardiac Death
Computation
sudden cardiac death
electrocardiogram signal
maximum overlap discrete wavelet packet transform
stacked autoencoders
deep learning
title A Computational Methodology Based on Maximum Overlap Discrete Wavelet Transform and Autoencoders for Early Prediction of Sudden Cardiac Death
title_full A Computational Methodology Based on Maximum Overlap Discrete Wavelet Transform and Autoencoders for Early Prediction of Sudden Cardiac Death
title_fullStr A Computational Methodology Based on Maximum Overlap Discrete Wavelet Transform and Autoencoders for Early Prediction of Sudden Cardiac Death
title_full_unstemmed A Computational Methodology Based on Maximum Overlap Discrete Wavelet Transform and Autoencoders for Early Prediction of Sudden Cardiac Death
title_short A Computational Methodology Based on Maximum Overlap Discrete Wavelet Transform and Autoencoders for Early Prediction of Sudden Cardiac Death
title_sort computational methodology based on maximum overlap discrete wavelet transform and autoencoders for early prediction of sudden cardiac death
topic sudden cardiac death
electrocardiogram signal
maximum overlap discrete wavelet packet transform
stacked autoencoders
deep learning
url https://www.mdpi.com/2079-3197/13/6/130
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