Colorectal Cancer Chemoprevention: Is This the Future of Colorectal Cancer Prevention?
Colorectal cancer (CRC) is presently one of the most common causes of cancer-related death in our setting and affects a great number of people each year. Screening strategies are commonly used but they do not seem enough to avoid CRC development or prevent completely its mortality. Because of this f...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/2012/327341 |
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| author | A. Manzano P. Pérez-Segura |
| author_facet | A. Manzano P. Pérez-Segura |
| author_sort | A. Manzano |
| collection | DOAJ |
| description | Colorectal cancer (CRC) is presently one of the most common causes of cancer-related death in our setting and affects a great number of people each year. Screening strategies are commonly used but they do not seem enough to avoid CRC development or prevent completely its mortality. Because of this fact other prevention strategies have gained interest in recent years. Chemoprevention seems to be an attractive option in this setting and several drugs have been studied in this field. This review is focused on salicylates, nonsteroidal anti-inflammatory drugs (NSAIDs) and cycloxygenase-2 inhibitors (COXIBs), whose mechanism of action could be directly related to colon cancer chemoprevention. |
| format | Article |
| id | doaj-art-aef3e8a29d0b4447a9df81d8da961746 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-aef3e8a29d0b4447a9df81d8da9617462025-02-03T05:50:43ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/327341327341Colorectal Cancer Chemoprevention: Is This the Future of Colorectal Cancer Prevention?A. Manzano0P. Pérez-Segura1Oncology Department, Hospital Clínico San Carlos, 28040 Madrid, SpainOncology Department, Hospital Clínico San Carlos, 28040 Madrid, SpainColorectal cancer (CRC) is presently one of the most common causes of cancer-related death in our setting and affects a great number of people each year. Screening strategies are commonly used but they do not seem enough to avoid CRC development or prevent completely its mortality. Because of this fact other prevention strategies have gained interest in recent years. Chemoprevention seems to be an attractive option in this setting and several drugs have been studied in this field. This review is focused on salicylates, nonsteroidal anti-inflammatory drugs (NSAIDs) and cycloxygenase-2 inhibitors (COXIBs), whose mechanism of action could be directly related to colon cancer chemoprevention.http://dx.doi.org/10.1100/2012/327341 |
| spellingShingle | A. Manzano P. Pérez-Segura Colorectal Cancer Chemoprevention: Is This the Future of Colorectal Cancer Prevention? The Scientific World Journal |
| title | Colorectal Cancer Chemoprevention: Is This the Future of Colorectal Cancer Prevention? |
| title_full | Colorectal Cancer Chemoprevention: Is This the Future of Colorectal Cancer Prevention? |
| title_fullStr | Colorectal Cancer Chemoprevention: Is This the Future of Colorectal Cancer Prevention? |
| title_full_unstemmed | Colorectal Cancer Chemoprevention: Is This the Future of Colorectal Cancer Prevention? |
| title_short | Colorectal Cancer Chemoprevention: Is This the Future of Colorectal Cancer Prevention? |
| title_sort | colorectal cancer chemoprevention is this the future of colorectal cancer prevention |
| url | http://dx.doi.org/10.1100/2012/327341 |
| work_keys_str_mv | AT amanzano colorectalcancerchemopreventionisthisthefutureofcolorectalcancerprevention AT pperezsegura colorectalcancerchemopreventionisthisthefutureofcolorectalcancerprevention |