Immune Recovery Uveitis
Immune Recovery Uveitis (IRU) is paradoxical clinical worsening of intraocular inflammatory reactions, attributable to improved immune functions after starting Highly Active Anti Retroviral Therapy (HAART) in HIV patients. It is the ophthalmological manifestation of Immune Reconstitution Inflammator...
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| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2015-04-01
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| Series: | Delhi Journal of Ophthalmology |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.7869/djo.114 |
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| _version_ | 1850204629718007808 |
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| author | S Balamurugan Ashish Khodifad |
| author_facet | S Balamurugan Ashish Khodifad |
| author_sort | S Balamurugan |
| collection | DOAJ |
| description | Immune Recovery Uveitis (IRU) is paradoxical clinical worsening of intraocular inflammatory reactions, attributable to improved immune functions after starting Highly Active Anti Retroviral Therapy (HAART) in HIV patients. It is the ophthalmological manifestation of Immune Reconstitution Inflammatory Syndrome (IRIS) which involves various body systems. With the use of HAART, the incidence of Opportunistic infections has declined significantly. However, the development of Immune Recovery Uveitis in these patients can cause substantial vision loss, thereby posing a new challenge. This article reviews the etiopathogenesis, risk factors, clinical presentation and management of IRU. |
| format | Article |
| id | doaj-art-aef2a9176a554b52ab6ded25e7533b76 |
| institution | OA Journals |
| issn | 0972-0200 2454-2784 |
| language | English |
| publishDate | 2015-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Delhi Journal of Ophthalmology |
| spelling | doaj-art-aef2a9176a554b52ab6ded25e7533b762025-08-20T02:11:15ZengWolters Kluwer Medknow PublicationsDelhi Journal of Ophthalmology0972-02002454-27842015-04-0125423323710.7869/djo.114Immune Recovery UveitisS BalamuruganAshish KhodifadImmune Recovery Uveitis (IRU) is paradoxical clinical worsening of intraocular inflammatory reactions, attributable to improved immune functions after starting Highly Active Anti Retroviral Therapy (HAART) in HIV patients. It is the ophthalmological manifestation of Immune Reconstitution Inflammatory Syndrome (IRIS) which involves various body systems. With the use of HAART, the incidence of Opportunistic infections has declined significantly. However, the development of Immune Recovery Uveitis in these patients can cause substantial vision loss, thereby posing a new challenge. This article reviews the etiopathogenesis, risk factors, clinical presentation and management of IRU.https://journals.lww.com/10.7869/djo.114immune recovery uveitishiv |
| spellingShingle | S Balamurugan Ashish Khodifad Immune Recovery Uveitis Delhi Journal of Ophthalmology immune recovery uveitis hiv |
| title | Immune Recovery Uveitis |
| title_full | Immune Recovery Uveitis |
| title_fullStr | Immune Recovery Uveitis |
| title_full_unstemmed | Immune Recovery Uveitis |
| title_short | Immune Recovery Uveitis |
| title_sort | immune recovery uveitis |
| topic | immune recovery uveitis hiv |
| url | https://journals.lww.com/10.7869/djo.114 |
| work_keys_str_mv | AT sbalamurugan immunerecoveryuveitis AT ashishkhodifad immunerecoveryuveitis |