The PEG-coated collagen patch Hemopatch® for hemostasis and dural sealing in neurosurgery
BackgroundPostoperative cerebrospinal fluid (CSF) leakage and bleeding are major postoperative complications that increase healthcare system costs. The use of Hemopatch® Sealing Hemostat has been shown to reduce the incidence of such postoperative complications. This technical report aims to provide...
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Frontiers Media S.A.
2025-08-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2025.1636372/full |
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| author | Jakob Rossmann Apio C. M. Antunes Guy G. Broc Danny T. M. Chan Se-Yi Chen Nicolas Dea Jacob Fairhall Pablo de Andrés Guijarro Nicola Montano Karl-Michael Schebesch Jake Timothy Vamsi Krishna Yerramneni |
| author_facet | Jakob Rossmann Apio C. M. Antunes Guy G. Broc Danny T. M. Chan Se-Yi Chen Nicolas Dea Jacob Fairhall Pablo de Andrés Guijarro Nicola Montano Karl-Michael Schebesch Jake Timothy Vamsi Krishna Yerramneni |
| author_sort | Jakob Rossmann |
| collection | DOAJ |
| description | BackgroundPostoperative cerebrospinal fluid (CSF) leakage and bleeding are major postoperative complications that increase healthcare system costs. The use of Hemopatch® Sealing Hemostat has been shown to reduce the incidence of such postoperative complications. This technical report aims to provide neurosurgeons with the best recommendations for the effective use of Hemopatch® as a hemostatic and dural sealant in cranial and spinal procedures.Material and methodsThe clinical experiences of 10 neurosurgeons from around the world regarding the use of Hemopatch® were evaluated using an online survey, followed by a hands-on preclinical workshop on adult pigs, which concluded with an in-depth discussion about the use of the patch.ResultsThe survey results provide an overview of how and when experts use different types of dural repair materials, including decision-making factors. During the workshop, Hemopatch® presented excellent tissue adherence on all evaluated defects. The new configuration of the patch showed improved tissue adherence, less curling of the patch, and easier removal of the gauze used for compression. Experts recommend using patches that overlap the defect for ≥1 cm. When closing defects that do not allow for a dried application site, Hemopatch® can be put on a dry gauze, which can be bent into a U-shape. This allows better targeting of the application site and enables immediate compression upon placement.ConclusionThe results provide information to improve the hands-on use of Hemopatch® as a dural sealant, therefore reducing the risk of postoperative complications such as CSF leaks, eventually reducing healthcare system costs. |
| format | Article |
| id | doaj-art-aeefdabb0b96484e9da9cd8545cead77 |
| institution | Kabale University |
| issn | 2296-875X |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj-art-aeefdabb0b96484e9da9cd8545cead772025-08-20T13:58:20ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2025-08-011210.3389/fsurg.2025.16363721636372The PEG-coated collagen patch Hemopatch® for hemostasis and dural sealing in neurosurgeryJakob Rossmann0Apio C. M. Antunes1Guy G. Broc2Danny T. M. Chan3Se-Yi Chen4Nicolas Dea5Jacob Fairhall6Pablo de Andrés Guijarro7Nicola Montano8Karl-Michael Schebesch9Jake Timothy10Vamsi Krishna Yerramneni11Department of Neurosurgery, Paracelsus Medical University, Nürnberg, GermanyNeurosurgery Department, Universidade Federal do Rio Grande do Sul and Hospital de Clínicas de Porto Alegre, Porto Alegre, BrazilNeurosurgery Department, American British Cowdray Hospital, Mexico City, MexicoDivision of Neurosurgery, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, ChinaDepartment of Neurosurgery, Chung Shan Medical University Hospital, Taichung City, TaiwanDivision of Neurosurgery, Department of Surgery, Vancouver General Hospital and the University of British Columbia, Vancouver, BC, CanadaBrainSpine Neurosurgery, Prince of Wales Hospital, Randwick, NSW, AustraliaNeurosurgery, Hospital Universitario Fundación Jiménez Díaz, Madrid, SpainDepartment of Neurosurgery, Fondazione Policlinico Universitario Agostino Gemelli IRCCS—Università Cattolica del Sacro Cuore, Rome, ItalyDepartment of Neurosurgery, Paracelsus Medical University, Nürnberg, Germany0Department of Neurosurgery, Nuffield Hospital, Leeds, United Kingdom1Department of Neurosurgery, Nizam’s Institute of Medical Sciences, Hyderabad, IndiaBackgroundPostoperative cerebrospinal fluid (CSF) leakage and bleeding are major postoperative complications that increase healthcare system costs. The use of Hemopatch® Sealing Hemostat has been shown to reduce the incidence of such postoperative complications. This technical report aims to provide neurosurgeons with the best recommendations for the effective use of Hemopatch® as a hemostatic and dural sealant in cranial and spinal procedures.Material and methodsThe clinical experiences of 10 neurosurgeons from around the world regarding the use of Hemopatch® were evaluated using an online survey, followed by a hands-on preclinical workshop on adult pigs, which concluded with an in-depth discussion about the use of the patch.ResultsThe survey results provide an overview of how and when experts use different types of dural repair materials, including decision-making factors. During the workshop, Hemopatch® presented excellent tissue adherence on all evaluated defects. The new configuration of the patch showed improved tissue adherence, less curling of the patch, and easier removal of the gauze used for compression. Experts recommend using patches that overlap the defect for ≥1 cm. When closing defects that do not allow for a dried application site, Hemopatch® can be put on a dry gauze, which can be bent into a U-shape. This allows better targeting of the application site and enables immediate compression upon placement.ConclusionThe results provide information to improve the hands-on use of Hemopatch® as a dural sealant, therefore reducing the risk of postoperative complications such as CSF leaks, eventually reducing healthcare system costs.https://www.frontiersin.org/articles/10.3389/fsurg.2025.1636372/fulldural sealanthemostasisspinalCSF leakageneurosurgerycranial |
| spellingShingle | Jakob Rossmann Apio C. M. Antunes Guy G. Broc Danny T. M. Chan Se-Yi Chen Nicolas Dea Jacob Fairhall Pablo de Andrés Guijarro Nicola Montano Karl-Michael Schebesch Jake Timothy Vamsi Krishna Yerramneni The PEG-coated collagen patch Hemopatch® for hemostasis and dural sealing in neurosurgery Frontiers in Surgery dural sealant hemostasis spinal CSF leakage neurosurgery cranial |
| title | The PEG-coated collagen patch Hemopatch® for hemostasis and dural sealing in neurosurgery |
| title_full | The PEG-coated collagen patch Hemopatch® for hemostasis and dural sealing in neurosurgery |
| title_fullStr | The PEG-coated collagen patch Hemopatch® for hemostasis and dural sealing in neurosurgery |
| title_full_unstemmed | The PEG-coated collagen patch Hemopatch® for hemostasis and dural sealing in neurosurgery |
| title_short | The PEG-coated collagen patch Hemopatch® for hemostasis and dural sealing in neurosurgery |
| title_sort | peg coated collagen patch hemopatch r for hemostasis and dural sealing in neurosurgery |
| topic | dural sealant hemostasis spinal CSF leakage neurosurgery cranial |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2025.1636372/full |
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